TWIST2

Gene Name		twist family bHLH transcription factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Factor Activity DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Transcription From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation Positive Regulation Of Keratinocyte Proliferation Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Embryonic Cranial Skeleton Morphogenesis Face Morphogenesis Cornea Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: MEF2C SREBF1 TCF12 TCF4
Entrez ID		117581
HPRD ID		09616
Ensembl ID		ENSG00000233608
Uniprot IDs		Q8WVJ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Regulation Of Triglyceride Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Neurogenesis Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Development Positive Regulation Of Lipid Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Muscle Structure Development Positive Regulation Of Protein Binding Regulation Of Neuron Differentiation Regulation Of Skeletal Muscle Tissue Development Regulation Of Secretion Transcription, DNA-templated Regulation Of Neurogenesis Tube Development Regulation Of Organ Growth RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Binding Regulation Of Cell Development Positive Regulation Of Cell Differentiation Response To Glucose Transcription From RNA Polymerase II Promoter Regulation Of Striated Muscle Tissue Development Regulation Of Lipid Biosynthetic Process Cellular Response To Starvation Regulation Of Protein Binding Organ Development Regulation Of Heart Contraction Catenin Import Into Nucleus Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cellular Localization Cellular Response To Nutrient Levels Response To Starvation RNA Metabolic Process Response To Carbohydrate Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Insulin Secretion
Tagcloud ?		aberrant acquire assessing biomarker cdk4 cervical contributions coupling defense emt federation gynecology initially invasion invasivity isoform mesenchymal metastasis motility obstetrics oncogenic overriding prognosis regulating senescence similarities undergo