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RASGRP4
Gene Name
RAS guanyl releasing protein 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Membrane
Molecular Function
Ras Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Diacylglycerol Binding
GTP-dependent Protein Binding
Biological Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Activation Of Phospholipase C Activity
Small GTPase Mediated Signal Transduction
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Cell Proliferation
Response To Extracellular Stimulus
Cell Growth
Myeloid Cell Differentiation
Positive Regulation Of Ras GTPase Activity
Positive Regulation Of Ras Protein Signal Transduction
Pathways
FCERI mediated NF-kB activation
Fc epsilon receptor (FCERI) signaling
Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
HRAS
RAP1A
Entrez ID
115727
HPRD ID
09540
Ensembl ID
ENSG00000171777
Uniprot IDs
Q8TDF6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Activation Of MAPKK Activity
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of ERK1 And ERK2 Cascade
Neurotrophin TRK Receptor Signaling Pathway
Ras Protein Signal Transduction
Neurotrophin Signaling Pathway
Activation Of Protein Kinase Activity
Positive Regulation Of Cell Projection Organization
Regulation Of Synaptic Transmission
Blood Coagulation
Hemostasis
Positive Regulation Of Ras GTPase Activity
Positive Regulation Of MAPK Cascade
Positive Regulation Of Rac Protein Signal Transduction
Positive Regulation Of Protein Kinase Activity
Cellular Response To Organonitrogen Compound
Regulation Of Cell Projection Organization
Positive Regulation Of Kinase Activity
Positive Regulation Of MiRNA Metabolic Process
Positive Regulation Of Ruffle Assembly
Regulation Of Ras GTPase Activity
Positive Regulation Of Transferase Activity
Cellular Response To Growth Factor Stimulus
Regulation Of Body Fluid Levels
Wound Healing
Response To Growth Factor
Regulation Of MAPK Cascade
Small GTPase Mediated Signal Transduction
Rap Protein Signal Transduction
Regulation Of Ras Protein Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of MiRNA Metabolic Process
Response To Wounding
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Vasculogenesis
Positive Regulation Of GTPase Activity
Regulation Of Protein Kinase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Nerve Growth Factor Signaling Pathway
Regulation Of GTPase Activity
Regulation Of Kinase Activity
Negative Regulation Of Rho GTPase Activity
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Actin Cytoskeleton Reorganization
Response To Organonitrogen Compound
Regulation Of Vasculogenesis
Positive Regulation Of Rap GTPase Activity
Positive Regulation Of Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud
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6j
accelerated
aml
aml1
bmt
c57bl
class
cloning
cmmol
conceivable
cooperates
flt3
hf6
immortalized
leukemia
leukemic
leukemogenesis
libraries
m2
marrow
mll
mpd
render
s291fsx300
screened
sept6
transduced
transduction
transplanted