FCHO2

Gene Name		FCH domain only 2
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Coated Pit Clathrin-coated Vesicle
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol Binding
	Biological Process	Membrane Invagination Clathrin Coat Assembly Clathrin-mediated Endocytosis Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: DAB2
Entrez ID		115548
HPRD ID		13319
Ensembl ID		ENSG00000157107
Uniprot IDs		Q0JRZ9
PDB IDs		2V0O
Enriched GO Terms of Interacting Partners?		Leading Edge Cell Differentiation Positive Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of Non-canonical Wnt Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Negative Regulation Of Androgen Receptor Signaling Pathway Pinocytosis Positive Regulation Of SMAD Protein Import Into Nucleus Positive Regulation Of Receptor Recycling Regulation Of SMAD Protein Import Into Nucleus Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Receptor Recycling Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Epithelial To Mesenchymal Transition Clathrin Coat Assembly Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Activation Of JUN Kinase Activity Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Excretion Regulation Of Protein Localization To Plasma Membrane Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Protein Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of JUN Kinase Activity Positive Regulation Of Proteasomal Protein Catabolic Process Membrane Budding Regulation Of JUN Kinase Activity Endoderm Development JNK Cascade Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Binding Positive Regulation Of Endocytosis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport
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