PGLYRP3

Description		peptidoglycan recognition protein 3
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GO Annotations	Cellular Component	Extracellular Region Membrane Protein-containing Complex
	Molecular Function	Protein Binding Zinc Ion Binding N-acetylmuramoyl-L-alanine Amidase Activity Peptidoglycan Immune Receptor Activity Peptidoglycan Binding Protein Heterodimerization Activity
	Biological Process	Immune System Process Immune Response Peptidoglycan Catabolic Process Detection Of Bacterium Killing Of Cells Of Another Organism Negative Regulation Of Type II Interferon Production Negative Regulation Of Natural Killer Cell Differentiation Involved In Immune Response Defense Response To Bacterium Innate Immune Response Defense Response To Gram-positive Bacterium Biological Process Involved In Interaction With Host Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Antimicrobial peptides
Drugs		2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE
Diseases
GWAS		Asthma ( 31619474) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)
Interacting Genes		4 interacting genes: CIDEB FAM209A HSD17B14 KRT34
Entrez ID		114771
HPRD ID		16297
Ensembl ID		ENSG00000159527
Uniprot IDs		Q96LB9
PDB IDs		1SK3 1SK4 1TWQ 2APH
Enriched GO Terms of Interacting Partners?		D-threo-aldose 1-dehydrogenase Activity COPI-coated Vesicle COPII Vesicle Coat Lipid Transfer Activity Lipid Droplet Fusion Very-low-density Lipoprotein Particle Assembly Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity L-fucose Catabolic Process Fucose Metabolic Process COPII-coated Vesicle Cargo Loading Execution Phase Of Apoptosis Phosphatidic Acid Binding Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly
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