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CHRNA5
Gene Name
cholinergic receptor, nicotinic, alpha 5 (neuronal)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Acetylcholine-gated Channel Complex
Cell Junction
Postsynaptic Membrane
Molecular Function
Acetylcholine-activated Cation-selective Channel Activity
Ligand-gated Ion Channel Activity
Acetylcholine Receptor Activity
Biological Process
Transport
Cation Transport
Signal Transduction
Synaptic Transmission
Ion Transmembrane Transport
Behavioral Response To Nicotine
Cation Transmembrane Transport
Pathways
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Acetylcholine Binding And Downstream Events
Activation of Nicotinic Acetylcholine Receptors
Postsynaptic nicotinic acetylcholine receptors
Presynaptic nicotinic acetylcholine receptors
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Highly calcium permeable nicotinic acetylcholine receptors
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Airflow obstruction (
22837378
)
Chronic obstructive pulmonary disease (
22080838
19300482
20173748
)
Lung adenocarcinoma (
19836008
)
Lung cancer (
18385676
18385738
18780872
)
Nicotine dependence (
18385739
)
Pulmonary function (
21946350
)
Serum albumin level (
23022100
)
Smoking behavior (
22832964
20418889
)
Protein-protein Interactions
1 interactors:
CHRNB4
Entrez ID
1138
HPRD ID
00334
Ensembl ID
ENSG00000169684
Uniprot IDs
P30532
Q6EWN4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Synaptic Transmission Involved In Micturition
Micturition
Behavioral Response To Nicotine
Synaptic Transmission, Cholinergic
Neuromuscular Synaptic Transmission
Response To Nicotine
Excretion
Regulation Of Smooth Muscle Contraction
Smooth Muscle Contraction
Regulation Of Neurotransmitter Secretion
Action Potential
Renal System Process
Response To Alkaloid
Regulation Of Muscle Contraction
Adult Behavior
Muscle Contraction
Locomotory Behavior
Muscle System Process
Regulation Of Membrane Potential
Regulation Of Synaptic Transmission
Single-organism Behavior
Tagcloud
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1x10
9x10
a3
accounts
adenocarcinoma
b4
chrnb3
clptm1l
conducting
cyp1a1
dependence
genetics
gwa
mediation
nicotine
nicotinic
personalized
rs1051730
rs12914385
rs2736100
rs2853676
rs31489
rs401681
smoking
snps
tert
variations