PIK3IP1

Description		phosphoinositide-3-kinase interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane
	Molecular Function	Endopeptidase Activity Signaling Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Inhibitor Activity
	Biological Process	Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways
Drugs
Diseases
GWAS		Fish- and plant-related diet ( 32066663) Metabolite levels ( 23823483) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 32888494)
Interacting Genes		7 interacting genes: MAGEA11 MFSD11 SLC35A1 TMEM218 UBQLN1 UBQLN2 UPK1B
Entrez ID		113791
HPRD ID		17518
Ensembl ID		ENSG00000100100
Uniprot IDs		Q96FE7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress CMP-N-acetylneuraminate Transmembrane Transporter Activity CMP-N-acetylneuraminate Transmembrane Transport Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Negative Regulation Of Store-operated Calcium Channel Activity Autophagosome Organization Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteasomal Protein Catabolic Process Apical Plasma Membrane Urothelial Plaque Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway CMP-N-acetylneuraminate Metabolic Process CMP-N-acetylneuraminate Biosynthetic Process Negative Regulation Of Clathrin-dependent Endocytosis Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Vacuole Organization Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Macroautophagy Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Pyrimidine Nucleotide-sugar Transmembrane Transport Nucleotide-sugar Transmembrane Transport N-acetylneuraminate Metabolic Process Regulation Of Toll-like Receptor 3 Signaling Pathway Aggrephagy Autophagy Negative Regulation Of Receptor Internalization Regulation Of Clathrin-dependent Endocytosis
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