VSIG4

Description		V-set and immunoglobulin domain containing 4
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GO Annotations	Cellular Component	Membrane Protein-containing Complex
	Molecular Function	Complement Component C3b Binding Protein Binding
	Biological Process	Immune System Process Complement Activation, Alternative Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Negative Regulation Of Macrophage Activation Innate Immune Response Negative Regulation Of Complement Activation, Alternative Pathway
Pathways
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Novel Interacting Genes		2 novel interacting genes: AP2B1 POLE
Interacting Genes		7 interacting genes: APP C3 FATE1 JAGN1 PDK2 TRIM72 VAMP5
Entrez ID		11326
HPRD ID		02286
Ensembl ID		ENSG00000155659
Uniprot IDs		Q9Y279
PDB IDs		2ICC 2ICE 2ICF 5IMK 5IML 8TE5 8TE6
Enriched GO Terms of Interacting Partners?		Neuron Remodeling Positive Regulation Of Endocytosis Secretion By Cell Secretion Vesicle-mediated Transport Clathrin-coated Pit Signal Sequence Binding Regulation Of Endocytosis Regulation Of Vesicle-mediated Transport Extrinsic Component Of Presynaptic Endocytic Zone Membrane Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Phosphorus Metabolic Process Monoatomic Ion Homeostasis Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Stress Amylin Binding Endosome To Plasma Membrane Transport Vesicle Neuron Maturation Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Receptor-mediated Endocytosis Receptor Ligand Activity Positive Regulation Of Receptor-mediated Endocytosis Monoatomic Cation Homeostasis Defense Response To Fungus Response To Fungus Regulation Of Calcium-mediated Signaling Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Response To Other Organism Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Immune Effector Process
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