TP53RK

Gene Name		TP53 regulating kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Cytosol Membrane
	Molecular Function	P53 Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Hydrolase Activity
	Biological Process	Protein Phosphorylation TRNA Processing Threonylcarbamoyladenosine Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CALCOCO2 MTUS2 TP53 TPRKB
Entrez ID		112858
HPRD ID		12276
Ensembl ID		ENSG00000172315
Uniprot IDs		Q5JZ02 Q96S44
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Negative Regulation Of Helicase Activity Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Mitochondrial DNA Repair Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation Viral Process DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Thymocyte Apoptotic Process Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior Mitochondrial DNA Metabolic Process Positive Regulation Of Histone Deacetylation Rhythmic Behavior Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Protein Oligomerization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process RRNA Transcription T Cell Lineage Commitment Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Deacetylation Cellular Response To Glucose Starvation Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Neuroblast Proliferation Photoperiodism Entrainment Of Circadian Clock Protein Import Into Nucleus, Translocation Regulation Of Protein Oligomerization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitochondrial Genome Maintenance Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Necroptotic Process
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