MRAP2

Description		melanocortin 2 receptor accessory protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding Signaling Receptor Regulator Activity Corticotropin Hormone Receptor Binding Type 3 Melanocortin Receptor Binding Type 4 Melanocortin Receptor Binding Type 5 Melanocortin Receptor Binding Identical Protein Binding Type 1 Melanocortin Receptor Binding
	Biological Process	Energy Reserve Metabolic Process Feeding Behavior Protein Localization To Plasma Membrane Energy Homeostasis Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 28991256) Whole brain grey matter density ( 31530798)
Interacting Genes		6 interacting genes: APH1A APP ISLR2 MC2R SGTA TMEM80
Entrez ID		112609
HPRD ID		12843
Ensembl ID		ENSG00000135324
Uniprot IDs		Q96G30
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Synaptic Membrane Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Corticotropin Receptor Activity TRC Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Melanocortin Receptor Activity BAT3 Complex Binding Positive Regulation Of Proteolysis Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Protein Catabolic Process Axon Choice Point Recognition Negative Regulation Of ERAD Pathway Gamma-secretase Complex Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion
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