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PACSIN2
Description
protein kinase C and casein kinase substrate in neurons 2
Image
GO Annotations
Cellular Component
Cytoplasm
Endosome
Early Endosome
Cytosol
Cytoskeleton
Plasma Membrane
Caveola
Cell-cell Junction
Adherens Junction
Focal Adhesion
Cilium
Membrane
Nuclear Speck
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Ruffle Membrane
Centriolar Satellite
Cell Projection
Recycling Endosome Membrane
Extracellular Exosome
Anchoring Junction
Glutamatergic Synapse
Molecular Function
Protein Binding
Phospholipid Binding
Cytoskeletal Protein Binding
Lipid Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Cadherin Binding
Phosphatidic Acid Binding
Biological Process
Cell Migration Involved In Sprouting Angiogenesis
Endocytosis
Cytoskeleton Organization
Actin Cytoskeleton Organization
Regulation Of Endocytosis
Protein Localization To Endosome
Negative Regulation Of Endocytosis
Cell Projection Morphogenesis
Modulation Of Chemical Synaptic Transmission
Caveola Assembly
Caveolin-mediated Endocytosis
Plasma Membrane Tubulation
Pathways
Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Mean platelet volume (
27863252
32888494
)
Platelet count (
27863252
32888494
)
Platelet distribution width (
27863252
32888494
)
Prostate cancer (SNP x SNP interaction) (
22219177
)
Interacting Genes
18 interacting genes:
DNM1
EHD1
EXOSC8
FASLG
GSC2
MECOM
MEOX2
PACSIN1
PACSIN3
PBX4
POT1
RIC8A
SHBG
SYNJ1
TERF1
TERF2IP
TRPV4
WASL
Entrez ID
11252
HPRD ID
05390
Ensembl ID
ENSG00000100266
Uniprot IDs
Q6FIA3
Q9UNF0
PDB IDs
3ABH
3ACO
3HAJ
3Q0K
Enriched GO Terms of Interacting Partners
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Shelterin Complex
Nuclear Telomere Cap Complex
G-rich Strand Telomeric DNA Binding
Telomere Capping
Positive Regulation Of Cellular Component Organization
Telomere Maintenance Via Telomerase
RNA-templated DNA Biosynthetic Process
Telomeric DNA Binding
Negative Regulation Of Cellular Component Organization
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Telomere Maintenance
Import Into Cell
Membrane Organization
Telomeric D-loop Disassembly
Regulation Of Cellular Component Organization
Positive Regulation Of Telomere Maintenance
Telomeric Loop Disassembly
Endocytosis
Negative Regulation Of Chromosome Organization
Plasma Membrane Tubulation
DNA Biosynthetic Process
Regulation Of Plasma Membrane Organization
Positive Regulation Of Organelle Organization
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomere Organization
Lipid Binding
Negative Regulation Of DNA Metabolic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Organelle Organization
Negative Regulation Of DNA Biosynthetic Process
Vesicle Budding From Membrane
Clathrin Coat Assembly Involved In Endocytosis
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
Negative Regulation Of Establishment Of RNA Localization To Telomere
Positive Regulation Of Shelterin Complex Assembly
Chromosome, Telomeric Region
Presynaptic Endocytosis
Synaptic Vesicle Endocytosis
Positive Regulation Of Endosome Organization
Positive Regulation Of DNA Strand Elongation
Positive Regulation Of Telomeric D-loop Disassembly
G-rich Single-stranded DNA Binding
Presynaptic Endocytic Zone
Osmosensor Activity
Blood Vessel Endothelial Cell Delamination
Tagcloud
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