PACSIN2

Gene Name		protein kinase C and casein kinase substrate in neurons 2
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Early Endosome Cytosol Cytoskeleton Caveola Cell-cell Junction Focal Adhesion Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane Membrane-bounded Vesicle Ruffle Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding Phosphatidic Acid Binding
	Biological Process	Actin Cytoskeleton Organization Regulation Of Endocytosis Protein Localization To Endosome Negative Regulation Of Endocytosis Cell Projection Morphogenesis Caveola Assembly Caveolin-mediated Endocytosis Membrane Tubulation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		12 interactors: DNM1 FASLG MEOX2 PACSIN1 PACSIN3 POT1 SHBG SYNJ1 TERF1 TERF2IP TRPV4 WASL
Entrez ID		11252
HPRD ID		05390
Ensembl ID		ENSG00000100266
Uniprot IDs		Q6FIA3 Q9UNF0
PDB IDs		3ABH 3ACO 3HAJ 3Q0K
Enriched GO Terms of Interacting Partners?		Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Regulation Of Cellular Component Organization Regulation Of Endocytosis Organelle Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Telomere Maintenance Endocytosis Negative Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Membrane Tubulation Regulation Of Telomerase Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of Organelle Organization Positive Regulation Of Protein Depolymerization Endomembrane System Organization Regulation Of Organelle Organization Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of Protein Complex Disassembly Endosome Organization Establishment Of Vesicle Localization Positive Regulation Of Cytoskeleton Organization Synaptic Vesicle Endocytosis Regulation Of Chromosome Organization Vesicle Localization Synaptic Vesicle Recycling Negative Regulation Of Endocytosis Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication DNA Replication Homeostatic Process Actin Filament Organization Vesicle-mediated Transport Establishment Of Organelle Localization Positive Regulation Of Synaptic Vesicle Uncoating Cortical Microtubule Organization Synaptic Vesicle Uncoating Positive Regulation Of DNA Strand Elongation Primary Spermatocyte Growth Osmosensory Signaling Pathway Negative Regulation Of DNA Recombination At Telomere Regulation Of Synaptic Vesicle Membrane Organization Regulation Of Microtubule Polymerization Or Depolymerization Cell-cell Signaling
Tagcloud ?		abolished apo bidirectional cd178 cd95 cd95l constructs correspond cytosolic fas fbp17 fingerprints formin fragments grb2 homology lysates mediator overexpressed polyproline precipitate precipitates respective sh3 stimulatory tail trafficking tubulin