RAB32

Description		RAB32, member RAS oncogene family
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Early Endosome Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Endomembrane System Membrane Phagocytic Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Early Endosome Lumen Vesicle Melanosome Membrane Melanosome Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Phagocytic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding AP-2 Adaptor Complex Binding AP-1 Adaptor Complex Binding AP-3 Adaptor Complex Binding BLOC-2 Complex Binding
	Biological Process	Intracellular Protein Transport Mitochondrion Organization Vesicle-mediated Transport Antigen Processing And Presentation Melanosome Organization Endosome To Melanosome Transport Protein Localization To Membrane Phagosome Maturation Melanosome Assembly
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Leprosy ( 22019778 25642632 27976721) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: CHM DDIT4L LRMDA PPP3R2 PRKAR2A
Entrez ID		10981
HPRD ID		06700
Ensembl ID		ENSG00000118508
Uniprot IDs		Q13637
PDB IDs		4CYM 4CZ2 5OEC 5OED 6FF8
Enriched GO Terms of Interacting Partners?		Protein Geranylgeranylation Rab-protein Geranylgeranyltransferase Complex Rab Geranylgeranyltransferase Activity Protein Prenylation Negative Regulation Of Calcium Ion Import Across Plasma Membrane Penetration Of Zona Pellucida Sperm Mitochondrial Sheath Positive Regulation Of Calcium Ion Import Across Plasma Membrane Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Protein Serine/threonine Phosphatase Complex Calcineurin Complex CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Nucleotide-activated Protein Kinase Complex Regulation Of Calcium Ion Import Across Plasma Membrane Negative Regulation Of Calcium Ion Import Protein Kinase A Catalytic Subunit Binding GDP-dissociation Inhibitor Activity Positive Regulation Of Calcineurin-NFAT Signaling Cascade Melanocyte Differentiation CAMP Binding Pigment Cell Differentiation Positive Regulation Of Calcium Ion Import Negative Regulation Of CAMP/PKA Signal Transduction Calcineurin-mediated Signaling Intracellular Signal Transduction
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