TRAFD1

Gene Name		TRAF-type zinc finger domain containing 1
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Gene Ontology Annotations	Cellular Component
	Molecular Function	Protein Binding Metal Ion Binding
	Biological Process	Response To Cytokine Negative Regulation Of Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Hemoglobin ( 19862010) Type 1 diabetes ( 17554300)
Protein-protein Interactions		4 interactors: HTT NGLY1 TRAF6 UBC
Entrez ID		10906
HPRD ID		10994
Ensembl ID		ENSG00000135148
Uniprot IDs		O14545
PDB IDs		2D9K
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Neural Plate Formation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Antigen Receptor-mediated Signaling Pathway Activation Of MAPK Activity Activation Of Innate Immune Response Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Protein Polyubiquitination Circadian Rhythm Morphogenesis Of Embryonic Epithelium Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Death Death Positive Regulation Of Innate Immune Response Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Endosomal Transport Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Protein Phosphatase Type 2A Activity Neurotrophin TRK Receptor Signaling Pathway
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