WDR3

Description		WD repeat domain 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome
	Molecular Function	RNA Binding SnoRNA Binding
	Biological Process	Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613)
Interacting Genes		4 interacting genes: CCAR2 HSPA13 NOP58 PDE10A
Entrez ID		10885
HPRD ID		16066
Ensembl ID		ENSG00000065183
Uniprot IDs		Q5TDG3 Q9UNX4
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Negative Regulation Of CGMP-mediated Signaling 3',5'-cGMP-stimulated Cyclic-nucleotide Phosphodiesterase Activity Cyclic-nucleotide Phosphodiesterase Activity CGMP Catabolic Process SnoRNA Localization Box C/D Methylation Guide SnoRNP Complex Positive Regulation Of DNA Damage Checkpoint DBIRD Complex CAMP Catabolic Process TFIID-class Transcription Factor Complex Binding Pre-snoRNP Complex Sno(s)RNA-containing Ribonucleoprotein Complex Mitochondrial Fragmentation Involved In Apoptotic Process Regulation Of Protein Deacetylation 3',5'-cyclic-AMP Phosphodiesterase Activity 3',5'-cyclic-nucleotide Phosphodiesterase Activity CGMP Metabolic Process 3',5'-cyclic-GMP Phosphodiesterase Activity CGMP Binding Cyclic Nucleotide Catabolic Process Regulation Of CGMP-mediated Signaling CAMP Binding Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway SnoRNA Binding Adenyl-nucleotide Exchange Factor Activity Positive Regulation Of Cell Cycle Checkpoint Regulation Of DNA Damage Checkpoint CAMP Metabolic Process Negative Regulation Of CAMP/PKA Signal Transduction Protein Refolding
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