WDR3

Name	WD repeat domain 3
Structure
Interactors	4 interactors: CCAR2 HSPA13 NOP58 PDE10A
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome
	Molecular Function	RNA Binding SnoRNA Binding
	Biological Process	Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis
Pathways	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
GWAS	Age-related hearing impairment ( 34108613 )
Entrez ID	10885
HPRD ID	16066
Ensembl ID	ENSG00000065183
Uniprot IDs	Q5TDG3 Q9UNX4
PDB IDs	7MQ8 7MQ9 7MQA
GO Terms Enriched among Interactors ?	Negative Regulation Of CGMP-mediated Signaling 3',5'-cGMP-stimulated Cyclic-nucleotide Phosphodiesterase Activity Cyclic-nucleotide Phosphodiesterase Activity CGMP Catabolic Process SnoRNA Localization Box C/D Methylation Guide SnoRNP Complex Positive Regulation Of DNA Damage Checkpoint DBIRD Complex CAMP Catabolic Process TFIID-class Transcription Factor Complex Binding Pre-snoRNP Complex Sno(s)RNA-containing Ribonucleoprotein Complex Mitochondrial Fragmentation Involved In Apoptotic Process Regulation Of Protein Deacetylation 3',5'-cyclic-AMP Phosphodiesterase Activity 3',5'-cyclic-nucleotide Phosphodiesterase Activity CGMP Metabolic Process 3',5'-cyclic-GMP Phosphodiesterase Activity CGMP Binding Cyclic Nucleotide Catabolic Process Regulation Of CGMP-mediated Signaling CAMP Binding Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway SnoRNA Binding Adenyl-nucleotide Exchange Factor Activity Positive Regulation Of Cell Cycle Checkpoint Regulation Of DNA Damage Checkpoint CAMP Metabolic Process Negative Regulation Of CAMP/PKA Signal Transduction Protein Refolding