CPLX1

Gene Name		complexin 1
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Gene Ontology Annotations	Cellular Component	Cytosol Dendrite Neuronal Cell Body Synapse Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex
	Molecular Function	Neurotransmitter Transporter Activity Syntaxin-1 Binding
	Biological Process	Exocytosis Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Insulin Secretion
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: AGTRAP CMTM5 SNAP25 STX1A VAMP2
Entrez ID		10815
HPRD ID		09233
Ensembl ID		ENSG00000168993
Uniprot IDs		F1T0G1 O14810
PDB IDs		3RK3 3RL0
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Vesicle Fusion Synaptic Vesicle Exocytosis Acid Secretion Organelle Fusion Dicarboxylic Acid Transport Neurotransmitter Secretion Synaptic Vesicle Transport Synaptic Vesicle Docking Positive Regulation Of Synaptic Transmission Membrane Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Energy Reserve Metabolic Process Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Regulation Of Insulin Secretion Establishment Of Vesicle Localization Pathogenesis Vesicle Organization Vesicle Localization Regulation Of Peptide Hormone Secretion Regulation Of Hormone Secretion Energy Derivation By Oxidation Of Organic Compounds Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Establishment Of Organelle Localization Exocytosis Calcium Ion-dependent Exocytosis Long-term Synaptic Potentiation Regulation Of Protein Secretion Generation Of Precursor Metabolites And Energy Organelle Localization Organic Anion Transport Vesicle Docking Involved In Exocytosis Secretion By Cell Vesicle Docking Synaptic Transmission Membrane Docking Regulation Of Protein Transport Secretion Regulation Of Secretion Anion Transport Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Regulation Of Exocytosis Membrane Organization Regulation Of Synaptic Plasticity Cell-cell Signaling
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