OGA

Description		O-GlcNAcase
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Hyalurononglucosaminidase Activity Hexosaminidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Identical Protein Binding [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase Activity Catalytic Activity, Acting On A Protein
	Biological Process	N-acetylglucosamine Metabolic Process Protein O-linked Glycosylation Glycoprotein Catabolic Process Protein Deglycosylation Glycoprotein Metabolic Process
Pathways
Drugs		Streptozocin
Diseases
GWAS
Interacting Genes		10 interacting genes: A2M C6 CDC37 CSNK2B DHX9 GSK3B MAST1 OGT PSEN2 RNF32
Entrez ID		10724
HPRD ID		04949
Ensembl ID		ENSG00000198408
Uniprot IDs		O60502
PDB IDs		2YDQ 5M7R 5M7S 5M7T 5M7U 5TKE 5UHK 5UHL 5UHO 5UHP 5UN8 5UN9 5VVO 5VVT 5VVU 5VVV 5VVX 6HKI 6PM9 7OU6 7YEH 8P0L 9BA8 9BA9
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase Regulator Activity Negative Regulation Of Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Viral Process Positive Regulation Of Translation Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Proteasomal Protein Catabolic Process Post-transcriptional Regulation Of Gene Expression Pyroptotic Inflammatory Response Rhythmic Process 3'-5' DNA/RNA Helicase Activity DNA-templated Viral Transcription Positive Regulation Of Nucleocytoplasmic Transport Regulatory Region RNA Binding Regulation Of Microtubule Anchoring At Centrosome Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Complement Activation, Lectin Pathway Phosphorylation Protein Phosphorylation Regulation Of Protein Catabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Cell Migration Regulation Of Proteolysis Regulation Of Protein Metabolic Process Chromatin DNA Binding Triplex DNA Binding Superior Temporal Gyrus Development TOR Signaling Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Scaffold Protein Binding HSP90-CDC37 Chaperone Complex Protein Serine/threonine Kinase Activity Regulation Of Immune Response Protease Binding Interleukin-8 Binding Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Viral Transcription Single-stranded 3'-5' DNA Helicase Activity
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