MERTK

Gene Name		MER proto-oncogene, tyrosine kinase
Image
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Rhabdomere
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Natural Killer Cell Differentiation Protein Phosphorylation Phagocytosis Cell Surface Receptor Signaling Pathway Cell-cell Signaling Spermatogenesis Blood Coagulation Peptidyl-tyrosine Phosphorylation Platelet Activation Secretion By Cell Substrate Adhesion-dependent Cell Spreading Apoptotic Cell Clearance Protein Kinase B Signaling Positive Regulation Of Phagocytosis Leukocyte Migration Negative Regulation Of Lymphocyte Activation Retina Development In Camera-type Eye Vagina Development
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Multiple sclerosis ( 21833088)
Protein-protein Interactions		8 interactors: BMPR2 GAS6 GRB2 IKBKG LMO4 NEDD4L TNK2 VAV1
Entrez ID		10461
HPRD ID		05269
Ensembl ID		ENSG00000153208
Uniprot IDs		E9PHX8 Q12866
PDB IDs		2DBJ 2P0C 3BPR 3BRB 3TCP
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Systemic Arterial Blood Pressure Cell Surface Receptor Signaling Pathway Intracellular Signal Transduction Regulation Of Cellular Component Organization Response To Stress Regulation Of Cell Activation Immune System Process Positive Regulation Of Protein Metabolic Process Viral Process Regulation Of Blood Pressure Negative Regulation Of Systemic Arterial Blood Pressure Cellular Response To Growth Factor Stimulus Immune Response Regulation Of Phosphorylation Regulation Of Endocytosis Response To Growth Factor Platelet Activation Endocytosis Positive Regulation Of Cellular Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphorus Metabolic Process Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Phagocytosis Fc Receptor Signaling Pathway Innate Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Migration Regulation Of Metabolic Process Positive Regulation Of Cell Activation Positive Regulation Of Phosphorylation Regulation Of Signaling Negative Regulation Of Blood Pressure Regulation Of Nitrogen Compound Metabolic Process Blood Circulation Response To External Stimulus Positive Regulation Of Immune System Process Cell Motility Positive Regulation Of Protein Modification Process Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Vesicle-mediated Transport Regulation Of Lymphocyte Activation Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Signaling
Tagcloud ?		apoptotic autoimmunity c1q clearance dehydrogenases e8 ebpbeta efferocytosis engulfed enhancement enhancing glucocorticoid glucocorticoids lxr lxrs macrophages mfg partly phagocytic phagocytosis ppardelta raldh1 raralpha retinaldehyde retinoids rxralpha seem sensing ucp2