IRAG1

Description		inositol 1,4,5-triphosphate receptor associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Platelet Dense Tubular Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	CGMP-mediated Signaling Negative Regulation Of Smooth Muscle Contraction Relaxation Of Vascular Associated Smooth Muscle
Pathways		cGMP effects
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: ASXL1
Interacting Genes		2 interacting genes: ITPR1 PRKG1
Entrez ID		10335
HPRD ID		05242
Ensembl ID		ENSG00000072952
Uniprot IDs		Q9Y6F6
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellularly Gated Calcium Channel Activity Platelet Dense Tubular Network Inositol 1,4,5-trisphosphate-gated Calcium Channel Activity Musculoskeletal Movement Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Epithelial Fluid Transport Platelet Dense Granule Membrane Calcium Ion Transmembrane Transporter Activity Platelet Dense Tubular Network Membrane Calcium Import Into The Mitochondrion Calcineurin Complex Voluntary Musculoskeletal Movement Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Calcium Channel Inhibitor Activity Cell Morphogenesis Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Inositol 1,4,5 Trisphosphate Binding Negative Regulation Of Amino Acid Transport CGMP-dependent Protein Kinase Activity Mitogen-activated Protein Kinase P38 Binding Negative Regulation Of Inositol Phosphate Biosynthetic Process Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Testosterone Biosynthetic Process Relaxation Of Smooth Muscle Negative Regulation Of Glutamate Secretion Relaxation Of Vascular Associated Smooth Muscle Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Platelet Aggregation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Peroxisome Proliferator Activated Receptor Binding Podocyte Development PR-DUB Complex Lung Saccule Development Bone Marrow Development Regulation Of Kidney Size Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway CGMP Binding G Protein-coupled Acetylcholine Receptor Signaling Pathway Mitochondrial Calcium Ion Transmembrane Transport Negative Regulation Of Calcium-mediated Signaling Regulation Of Biological Quality Regulation Of Secretion By Cell Positive Regulation Of Circadian Rhythm Relaxation Of Muscle Collateral Sprouting Negative Regulation Of Muscle Contraction Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
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