TRIM13

Description		tripartite motif containing 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Endoplasmic Reticulum
	Molecular Function	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity Ubiquitin-like Protein Ligase Activity
	Biological Process	Immune System Process Positive Regulation Of Macroautophagy Protein Ubiquitination Negative Regulation Of Viral Transcription ERAD Pathway Positive Regulation Of Canonical NF-kappaB Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Suppression Of Viral Release By Host Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein Autoubiquitination Endoplasmic Reticulum Mannose Trimming
Pathways		ER Quality Control Compartment (ERQC)
Drugs		Etorphine Diprenorphine Dihydromorphine
Diseases
GWAS		Diastolic blood pressure ( 30224653) Height ( 23563607) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		16 interacting genes: AKT1 ARHGDIA CCNA1 CDC34 GMCL1 MDM2 ROBO2 UBE2C UBE2D2 UBE2D3 UBE2E1 UBE2H UBE2K UBE2L3 UBE2L6 UBE2N
Entrez ID		10206
HPRD ID		10414
Ensembl ID		ENSG00000204977
Uniprot IDs		O60858
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification Macromolecule Catabolic Process Protein K48-linked Ubiquitination Proteolysis Protein K11-linked Ubiquitination Protein Modification Process Transferase Activity Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Binding Proteasomal Protein Catabolic Process Nucleotide Binding Protein Metabolic Process Protein Catabolic Process Ubiquitin-like Protein Transferase Activity Ubiquitin Ligase Complex Nucleus ISG15 Transferase Activity Cytosol ISG15-protein Conjugation Cell Cycle Phase Transition Free Ubiquitin Chain Polymerization Protein Monoubiquitination Positive Regulation Of Protein Modification Process Regulation Of Protein Ubiquitination Ubiquitin-protein Transferase Activator Activity Protein Autoubiquitination Positive Regulation Of Protein Metabolic Process Regulation Of Post-translational Protein Modification Positive Regulation Of Mitotic Cell Cycle Phase Transition Ubiquitin Binding Nucleoplasm Positive Regulation Of Protein Ubiquitination Macromolecule Metabolic Process Ubiquitin Protein Ligase Binding Positive Regulation Of Cell Cycle Phase Transition Response To Ether Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Mitotic Cell Cycle Cellular Response To Hormone Stimulus Regulation Of Protein Modification Process Negative Regulation Of Protein Maturation
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