PLXNC1

Description		plexin C1
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GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Membrane Cerebellar Climbing Fiber To Purkinje Cell Synapse
	Molecular Function	Signaling Receptor Binding Protein Binding Semaphorin Receptor Activity
	Biological Process	Cell Adhesion Negative Regulation Of Cell Adhesion Synapse Assembly Regulation Of Cell Shape Regulation Of Cell Migration Positive Regulation Of Axonogenesis Semaphorin-plexin Signaling Pathway Regulation Of Synapse Pruning
Pathways		Other semaphorin interactions
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Asthma ( 31959851 32296059 34103634) Blood protein levels ( 30072576) Diastolic blood pressure ( 30578418) Femur bone mineral density x serum urate levels interaction ( 34046847) Major depressive disorder ( 29317602) Multiple sclerosis ( 31604244) Pulse pressure ( 30578418) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Novel Interacting Genes		1 novel interacting genes: CKAP4
Interacting Genes		1 interacting genes: SEMA7A
Entrez ID		10154
HPRD ID		05036
Ensembl ID		ENSG00000136040
Uniprot IDs		O60486
PDB IDs		3KUZ 3NVN 3NVQ 6VXK
Enriched GO Terms of Interacting Partners?		Olfactory Lobe Development
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