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TRAF4 and NUDT16L1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TRAF4
NUDT16L1
Description
TNF receptor associated factor 4
nudix hydrolase 16 like 1
Image
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Bicellular Tight Junction
Membrane
Perinuclear Region Of Cytoplasm
Anchoring Junction
Nucleus
Molecular Function
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Signaling Adaptor Activity
Identical Protein Binding
Metal Ion Binding
WW Domain Binding
RNA Binding
Protein Binding
SnoRNA Binding
Protein Homodimerization Activity
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity
Phosphodiesterase Decapping Endonuclease Activity
Biological Process
Immune System Process
Apoptotic Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
Respiratory Gaseous Exchange By Respiratory System
Respiratory Tube Development
Regulation Of Apoptotic Process
Regulation Of Canonical NF-kappaB Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
MRNA Catabolic Process
Sno(s)RNA Catabolic Process
Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Drugs
Diseases
GWAS
Interacting Genes
137 interacting genes:
ABI3
ACTMAP
ALKBH4
ANXA1
AR
ATOSB
ATOX1
BACH2
BAHD1
BANP
BCKDK
BCL6B
BEGAIN
BEX3
BYSL
CALCOCO2
CAV1
CBL
CBLC
CCHCR1
CENPE
CEP85
CHEK1
CHUK
DISC1
DNM2
DPEP2NB
DTX3
EXOC7
EYA2
EZHIP
FAM90A1
FAT1
FBXL18
FRS3
FTH1
GOLGA2
GOLGA6A
GOLGA6L9
GORASP1
GORASP2
GPRASP1
HEY2
HGS
HMG20A
HOMEZ
HOXA1
HOXB5
IRAK1
IRS1
ISYNA1
KANK2
KANSL1
KDM1A
KRT31
KRT36
LENG8
LNX1
LTBR
MAGEC2
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NHERF2
NOS1AP
NPAS2
NTRK1
NUDT16L1
OGT
PCSK5
PDE4DIP
PHLDA1
PICK1
PKD1P1
PLAGL2
PLEKHA7
PLSCR1
POLR2J
POLR2J3
PSMC3
QARS1
RAD54L2
RBPMS
REXO1L6P
RNF114
RNF144B
RNF4
RPS6KB1
SF3B4
SIGLEC7
SMURF1
SMURF2
SNRPB
SORBS2
SPDL1
SUMO1
TARBP2
TAX1BP1
TBC1D7
TBC1D8
TFAP4
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM27
TRIM37
TSGA10IP
TYK2
UBC
UBE2D1
UBE2I
UBL4A
UBL4B
USP7
VPS52
WBP11
WWP1
WWP2
ZBTB16
ZBTB26
ZC3H12C
ZMYM5
ZNF177
ZNF275
ZNF3
ZNF512B
ZNF559-ZNF177
ZNF581
ZNF620
ZNF688
ZNF784
ZNF835
ZRANB1
53 interacting genes:
APP
CABP2
CEBPA
ERBB2
FBXO7
HNRNPF
HNRNPH1
IKZF3
INCA1
KRT31
LRRK1
METTL17
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR141
MIR145
MIR18B
MIR200C
MIR21
MIR25
MIR31
MIR34A
MIR34B
MIR363
MIR451A
MIR7-3
MIR9-1
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4L
NEK6
NTAQ1
PNMA1
RECK
SMARCD1
TRAF2
TRAF4
TRAF7
TRIM68
ZRANB1
Entrez ID
9618
84309
HPRD ID
03915
15309
Ensembl ID
ENSG00000076604
ENSG00000168101
Uniprot IDs
Q9BUZ4
B2RD96
K7ENA3
Q9BRJ7
W4VSQ8
PDB IDs
2EOD
2YUC
3ZJB
4K8U
4M4E
5YC1
3KVH
5ZCJ
6CO1
6D0L
8U3S
Enriched GO Terms of Interacting Partners
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Protein Binding
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Protein Modification Process
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Cytosol
Protein Modification By Small Protein Conjugation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Ubiquitination
Regulation Of Transcription By RNA Polymerase II
Ubiquitin-protein Transferase Activity
Regulation Of Gene Expression
Ubiquitin Protein Ligase Activity
Post-translational Protein Modification
Negative Regulation Of RNA Metabolic Process
Modification-dependent Protein Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Surface Toll-like Receptor Signaling Pathway
Identical Protein Binding
Ubiquitin-dependent Protein Catabolic Process
Protein Metabolic Process
Cell Surface Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of Macromolecule Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Cytoplasm
Positive Regulation Of Metabolic Process
Regulation Of Protein Modification Process
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Ubiquitination
Regulation Of Post-translational Protein Modification
Regulation Of Protein Ubiquitination
PML Body
Regulation Of Programmed Cell Death
Negative Regulation Of Macromolecule Biosynthetic Process
Signaling Adaptor Activity
Zinc Ion Binding
Proteolysis
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Catabolic Process
Positive Regulation Of Protein Metabolic Process
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MiRNA-mediated Gene Silencing By MRNA Destabilization
MRNA 3'-UTR Binding
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
MRNA Destabilization
Negative Regulation Of Biosynthetic Process
RNA Destabilization
Negative Regulation Of Metabolic Process
Positive Regulation Of MRNA Catabolic Process
Extracellular Vesicle
Regulation Of MRNA Stability
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Cell Migration
Regulation Of RNA Stability
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
Regulation Of Gene Expression
Regulation Of Metabolic Process
Positive Regulation Of Catabolic Process
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Translation
Regulation Of MRNA Metabolic Process
Regulation Of Translation
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Extracellular Space
Regulation Of Signal Transduction
Regulation Of Developmental Process
Regulation Of Locomotion
Regulation Of Cell Migration
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Negative Regulation Of Multicellular Organismal Process
Regulation Of Cell Motility
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Protein Metabolic Process
Negative Regulation Of Cytokine Production
Regulation Of Cellular Response To Growth Factor Stimulus
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