MUC16 and SUN2

		MUC16	SUN2
Description		mucin 16, cell surface associated	Sad1 and UNC84 domain containing 2
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GO Annotations	Cellular Component	Extracellular Region Golgi Lumen Plasma Membrane External Side Of Plasma Membrane Membrane Vesicle Extracellular Exosome	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Nuclear Envelope Nuclear Inner Membrane Endosome Endosome Membrane Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity
	Biological Process	Cell Adhesion	Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane
Pathways		Defective GALNT3 causes HFTC Defective C1GALT1C1 causes TNPS Defective GALNT12 causes CRCS1 Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis	Meiotic synapsis
Drugs		Dimethyl sulfoxide Oregovomab
Diseases
GWAS		Asthma ( 30929738 32296059) Hepcidin/transferrin saturation ratio ( 27846281) Serum cancer antigen 125 (CA 125) levels ( 31666285) Tourette syndrome ( 30818990)	Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		5 interacting genes: LGALS1 MSLN ODAD3 SUN2 UBC	16 interacting genes: ALS2 APOBEC3C HGS MAFF MUC16 NRM PAEP PRPF6 PSMC2 RAB5B RASD2 RGS2 RPS20 SH3BP1 SRSF10 TXN2
Entrez ID		94025	25777
HPRD ID		07548	15611
Ensembl ID		ENSG00000181143	ENSG00000100242
Uniprot IDs		A0AAG2UXK0 B3KY81 Q8WXI7	B0QY60 B0QY64 B4E2A6 Q9UH99
PDB IDs		7SA9 8GKL 8VM1 8VRS	3UNP 4DXR 4DXS 4DXT 4FI9 6WMD 6WME 6WMF 6WMG
Enriched GO Terms of Interacting Partners?		Lactose Binding Positive Regulation Of Dendritic Cell Differentiation Galectin Complex Negative Regulation Of T-helper 17 Cell Lineage Commitment Plasma Cell Differentiation Nuclear Migration Along Microfilament Microtubule-based Transport Nuclear Migration Along Microtubule Nuclear Matrix Organization Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Cytoskeleton-nuclear Membrane Anchor Activity Nuclear Matrix Anchoring At Nuclear Membrane Determination Of Heart Left/right Asymmetry Outer Dynein Arm Docking Complex	Endosome Organization Spliceosomal Tri-snRNP Complex Assembly
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