ZMYND12 and PRR5-ARHGAP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMYND12	PRR5-ARHGAP8
Description		zinc finger MYND-type containing 12	PRR5-ARHGAP8 readthrough
Image			No pdb structure
GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Sperm Axoneme Assembly Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS			Body mass index ( 28552196) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Major depressive disorder ( 27777418) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Weight ( 28552196)
Interacting Genes		81 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 C1orf50 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	3 interacting genes: CYGB GRB2 ZMYND12
Entrez ID		84217	553158
HPRD ID		15740	18688
Ensembl ID		ENSG00000066185	ENSG00000248405
Uniprot IDs		B4DX70 Q9H0C1	B1AHC3
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity	Guanyl-nucleotide Exchange Factor Adaptor Activity Grb2-EGFR Complex Negative Regulation Of Hepatic Stellate Cell Activation Nitric Oxide Catabolic Process Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor Catalase Activity Carbon Monoxide Binding Superoxide Dismutase Activity Nitrite Reductase Activity Neurotrophin TRKA Receptor Binding Branching Involved In Labyrinthine Layer Morphogenesis Insulin Receptor Substrate Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Negative Regulation Of Collagen Biosynthetic Process Oxygen Carrier Activity Removal Of Superoxide Radicals Negative Regulation Of Fibroblast Migration Oxygen Transport Schwann Cell Development Epidermal Growth Factor Receptor Binding Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity COP9 Signalosome Insulin-like Growth Factor Receptor Signaling Pathway Ephrin Receptor Binding Regulation Of Cell Activation Sperm Axoneme Assembly Nitric Oxide Metabolic Process Peroxidase Activity Antioxidant Activity Reactive Nitrogen Species Metabolic Process Oxygen Binding Endodermal Cell Differentiation Vesicle Membrane
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