PRR5-ARHGAP8 and ZMYND12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRR5-ARHGAP8	ZMYND12
Description		PRR5-ARHGAP8 readthrough	zinc finger MYND-type containing 12
Image		No pdb structure
GO Annotations	Cellular Component		Cilium Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function		Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process		Sperm Axoneme Assembly Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Major depressive disorder ( 27777418) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Weight ( 28552196)
Interacting Genes		3 interacting genes: CYGB GRB2 ZMYND12	81 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 C1orf50 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414
Entrez ID		553158	84217
HPRD ID		18688	15740
Ensembl ID		ENSG00000248405	ENSG00000066185
Uniprot IDs		B1AHC3	B4DX70 Q9H0C1
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Guanyl-nucleotide Exchange Factor Adaptor Activity Grb2-EGFR Complex Negative Regulation Of Hepatic Stellate Cell Activation Nitric Oxide Catabolic Process Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor Catalase Activity Carbon Monoxide Binding Superoxide Dismutase Activity Nitrite Reductase Activity Neurotrophin TRKA Receptor Binding Branching Involved In Labyrinthine Layer Morphogenesis Insulin Receptor Substrate Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Negative Regulation Of Collagen Biosynthetic Process Oxygen Carrier Activity Removal Of Superoxide Radicals Negative Regulation Of Fibroblast Migration Oxygen Transport Schwann Cell Development Epidermal Growth Factor Receptor Binding Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity COP9 Signalosome Insulin-like Growth Factor Receptor Signaling Pathway Ephrin Receptor Binding Regulation Of Cell Activation Sperm Axoneme Assembly Nitric Oxide Metabolic Process Peroxidase Activity Antioxidant Activity Reactive Nitrogen Species Metabolic Process Oxygen Binding Endodermal Cell Differentiation Vesicle Membrane	Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity
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