UXT and RCAN1

Number of citations of the paper that reports this interaction (PubMedID 15264020)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		UXT	RCAN1
Description		ubiquitously expressed prefoldin like chaperone	regulator of calcineurin 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton Mediator Complex Protein-containing Complex Protein Folding Chaperone Complex RPAP3/R2TP/prefoldin-like Complex	Nucleus Cytoplasm
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Nucleic Acid Binding Protein Phosphatase Inhibitor Activity Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Protein Stabilization	Response To Ischemia Response To Stress Response To Oxidative Stress Skeletal Muscle Tissue Development Short-term Memory Response To Mechanical Stimulus Calcium-mediated Signaling Locomotion Involved In Locomotory Behavior Calcineurin-NFAT Signaling Cascade Response To Estrogen Skeletal Muscle Fiber Development Negative Regulation Of Smooth Muscle Cell Differentiation Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Transcriptional Regulation by E2F6
Drugs			Dipyridamole
Diseases
GWAS			Cancer ( 29299148) Rheumatoid arthritis ( 23143596 24390342 30423114) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		29 interacting genes: APP AR CECR2 DYNLT1 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 TXNIP VHL	29 interacting genes: APP ATP5PO BTRC CBR3 CXXC5 DSCAM E2F3 GSK3B IL10RB ITSN1 KCNE1 MAP3K3 MAPK3 NEUROD2 PICK1 PPP3CA PPP3CB PPP3R1 PRDM4 PTPRD SF3A2 SON SOX10 SOX9 SPARCL1 USP22 UXT ZNF292 ZNF350
Entrez ID		8409	1827
HPRD ID		02209	04226
Ensembl ID		ENSG00000126756	ENSG00000159200
Uniprot IDs		Q9UBK9	B7Z1F0 E9PDJ2 P53805 Q6FGP2 Q6ZMM3 V9GYW9
PDB IDs			6UUQ
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Amyloid Fibril Formation Identical Protein Binding Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis	Regulation Of Calcium-mediated Signaling Modulation Of Chemical Synaptic Transmission Positive Regulation Of Calcium-mediated Signaling Regulation Of Transcription By RNA Polymerase II Glial Cell Development Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Positive Regulation Of Cellular Component Organization Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Protein Serine/threonine Phosphatase Complex Regulation Of Calcineurin-mediated Signaling Positive Regulation Of Calcium Ion Import Across Plasma Membrane Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Calcium Ion Import Regulation Of Calcium Ion Import Across Plasma Membrane Glutamatergic Synapse Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Calcineurin-NFAT Signaling Cascade Calcineurin-NFAT Signaling Cascade Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Intracellular Signaling Cassette Cell Development Regulation Of Endocytosis Positive Regulation Of Calcium Ion Import Protein Dimerization Activity Calcineurin-mediated Signaling Regulation Of Cellular Component Organization Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Synaptic Plasticity Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Monoatomic Ion Transport Regulation Of Vesicle-mediated Transport Calmodulin-dependent Protein Phosphatase Activity Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Biosynthetic Process Negative Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Cation Transmembrane Transport
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