UXT and CECR2

Number of citations of the paper that reports this interaction (PubMedID 12762840)
65

Data Source:
HPRD (two hybrid, in vitro)

		UXT	CECR2
Description		ubiquitously expressed prefoldin like chaperone	CECR2 histone acetyl-lysine reader
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton Mediator Complex Protein-containing Complex Protein Folding Chaperone Complex RPAP3/R2TP/prefoldin-like Complex	Euchromatin Nucleus ISWI-type Complex CERF Complex
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Protein Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Protein Stabilization	Neural Fold Formation Neural Tube Closure Apoptotic DNA Fragmentation Chromatin Organization Chromatin Remodeling Cytoskeleton Organization Single Fertilization Vesicle-mediated Transport Neural Tube Development Inner Ear Receptor Cell Stereocilium Organization Cytoskeleton-dependent Cytokinesis Cochlea Development Execution Phase Of Apoptosis
Pathways		Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Interacting Genes		29 interacting genes: APP AR CECR2 DYNLT1 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 TXNIP VHL	3 interacting genes: LRPPRC PRICKLE1 UXT
Entrez ID		8409	27443
HPRD ID		02209	10463
Ensembl ID		ENSG00000126756	ENSG00000099954
Uniprot IDs		Q9UBK9	B7WPH3 Q9BXF3
PDB IDs			3NXB 5V84 8RU1
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Amyloid Fibril Formation Identical Protein Binding Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis	Cytoskeleton-dependent Intracellular Transport Mitochondrion Transport Along Microtubule Establishment Of Mitochondrion Localization Beta-tubulin Binding Mitochondrion Localization Organelle Transport Along Microtubule Microtubule-based Process Anterior Visceral Endoderm Cell Migration Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Polarized Secretion Of Basement Membrane Proteins In Epithelium Cell Trailing Edge Transport Along Microtubule Intracellular Transport Negative Regulation Of Mitochondrial MRNA Catabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process Establishment Of Bipolar Cell Polarity Involved In Cell Morphogenesis Focal Adhesion Disassembly Actin Filament Binding Microtubule-based Transport Extracellular Matrix Constituent Secretion Tear Secretion Negative Regulation Of RNA Metabolic Process Microtubule Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Localization Establishment Of Organelle Localization Establishment Of Localization In Cell Mitochondrial MRNA Polyadenylation Embryonic Nail Plate Morphogenesis Gene Expression Maintenance Of Postsynaptic Density Structure Mitochondrial RNA Catabolic Process Microtubule-based Movement Maintenance Of Postsynaptic Specialization Structure Cornea Development In Camera-type Eye RPAP3/R2TP/prefoldin-like Complex Primitive Streak Formation Microtubule Cytoskeleton Organization Organelle Localization Negative Regulation Of Cardiocyte Differentiation Eyelid Development In Camera-type Eye Regulation Of Postsynaptic Density Assembly Negative Regulation Of Macromolecule Metabolic Process Regulation Of Mitochondrial Translation Post-anal Tail Morphogenesis Embryonic Brain Development Regulation Of Postsynaptic Specialization Assembly Regulation Of Excitatory Synapse Assembly Postsynaptic Density Organization Negative Regulation Of Metabolic Process
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