STK40 and SNIP1

		STK40	SNIP1
Description		serine/threonine kinase 40	Smad nuclear interacting protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Cytosol U2-type Precatalytic Spliceosome
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	RNA Binding MRNA Binding Protein Binding Transcription Regulator Inhibitor Activity
	Biological Process	Respiratory System Process Glycogen Metabolic Process Regulation Of Gene Expression Lung Development Multicellular Organism Growth Negative Regulation Of Apoptotic Process Regulation Of MAPK Cascade Lung Alveolus Development Lung Morphogenesis	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing MiRNA Processing Negative Regulation Of Canonical NF-kappaB Signal Transduction U2-type Prespliceosome Assembly
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Neutrophil count ( 32888494)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		7 interacting genes: APP COPS6 LRRK2 NEDD4L POLA2 SLIRP SNIP1	57 interacting genes: AKIRIN1 CDK6 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG EVA1B FAF1 GMEB1 GYS1 HIPK1 HIPK3 JUN KRTAP10-6 MAX MYC NFATC2 OXSM PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 POU3F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SH3D21 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM2 SRRM4 STK3 STK40 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451 ZNF496
Entrez ID		83931	79753
HPRD ID		11359	06999
Ensembl ID		ENSG00000196182	ENSG00000163877
Uniprot IDs		Q8N2I9	B1AK66 Q8TAD8
PDB IDs		5L2Q	5Z56 5Z57 5Z58 6FF7 7ABG 7ABH 7ABI 7DVQ 8I0P 8I0R
Enriched GO Terms of Interacting Partners?		Golgi-associated Vesicle Positive Regulation Of Endocytosis Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Positive Regulation Of Protein Catabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Neuromuscular Junction Development Synapse Organization Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Macromolecule Metabolic Process Regulation Of Synapse Organization Modulation Of Excitatory Postsynaptic Potential Regulation Of Membrane Depolarization Regulation Of Endocytosis Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Acetylcholine Receptor Activator Activity Positive Regulation Of Tumor Necrosis Factor Production Regulation Of Membrane Potential Regulation Of Response To Endoplasmic Reticulum Stress Endocytosis Regulation Of Calcium-mediated Signaling Lipoprotein Particle Cell Junction Organization Positive Regulation Of Protein Import Negative Regulation Of Mitochondrial MRNA Catabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Beta-catenin Destruction Complex Binding Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production	Regulation Of Nucleobase-containing Compound Metabolic Process PML Body Chromatin Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process SUMO Transferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Sumoylation SUMO Ligase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Binding Nuclear Speck DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Metabolic Process Regulation Of MiRNA Metabolic Process Nucleobase-containing Compound Metabolic Process
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