SNIP1 and SON

Number of citations of the paper that reports this interaction (PubMedID 30404004)
57

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		SNIP1	SON
Description		Smad nuclear interacting protein 1	SON DNA and RNA binding protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Cytosol U2-type Precatalytic Spliceosome	Nucleus Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding Transcription Regulator Inhibitor Activity	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing MiRNA Processing Negative Regulation Of Canonical NF-kappaB Signal Transduction U2-type Prespliceosome Assembly	Microtubule Cytoskeleton Organization Mitotic Cytokinesis MRNA Processing RNA Splicing Negative Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cell Cycle
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Heel bone mineral density x serum urate levels interaction ( 34046847) Psoriasis ( 25854761)
Interacting Genes		57 interacting genes: AKIRIN1 CDK6 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG EVA1B FAF1 GMEB1 GYS1 HIPK1 HIPK3 JUN KRTAP10-6 MAX MYC NFATC2 OXSM PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 POU3F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SH3D21 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM2 SRRM4 STK3 STK40 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451 ZNF496	11 interacting genes: CLIP4 KCNJ15 MAGEA6 PEA15 PRPF40A RCAN1 SNIP1 TRIP6 VHL YWHAB YWHAG
Entrez ID		79753	6651
HPRD ID		06999	01678
Ensembl ID		ENSG00000163877	ENSG00000159140
Uniprot IDs		B1AK66 Q8TAD8	J3QSZ5 P18583 Q6ZRV7
PDB IDs		5Z56 5Z57 5Z58 6FF7 7ABG 7ABH 7ABI 7DVQ 8I0P 8I0R	7CIQ 7CIR 7CIS 7DYN
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process PML Body Chromatin Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process SUMO Transferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Sumoylation SUMO Ligase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Binding Nuclear Speck DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Metabolic Process Regulation Of MiRNA Metabolic Process Nucleobase-containing Compound Metabolic Process	Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Phosphatase Inhibitor Activity Protein Sequestering Activity
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