DRC3 and ELAC2

		DRC3	ELAC2
Description		dynein regulatory complex subunit 3	elaC ribonuclease Z 2
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid
	Molecular Function	Protein Binding	RNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity TRNA-specific Ribonuclease Activity Hydrolase Activity 3'-tRNA Processing Endoribonuclease Activity Metal Ion Binding
	Biological Process		TRNA Processing TRNA Decay TRNA 3'-end Processing Mitochondrial TRNA Processing Mitochondrial TRNA 3'-end Processing
Pathways			tRNA processing in the nucleus tRNA processing in the mitochondrion rRNA processing in the mitochondrion tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis
Drugs
Diseases
GWAS			Squamous cell lung carcinoma ( 28604730)
Interacting Genes		12 interacting genes: EIF3E ELAC2 FUNDC2 GID4 MFHAS1 PLAGL1 SMCR8 SOD2 SPECC1 ZNF250 ZNF287 ZNF624	12 interacting genes: ASCC2 CTBP1 CTBP2 CUX1 DRC3 GID4 GOLM1 NDUFA7 RING1 RNF10 SMAD2 SUMO2
Entrez ID		83450	60528
HPRD ID		13181	05641
Ensembl ID		ENSG00000171962	ENSG00000006744
Uniprot IDs		B3KSC6 Q9H069	A0A0S2Z5M8 Q9BQ52
PDB IDs		8J07	8CBL 8RR1 8RR3 8RR4 8Z0P 8Z1F 8Z1G 9EY0 9EY1 9EY2
Enriched GO Terms of Interacting Partners?			Ribosome-associated Ubiquitin-dependent Protein Catabolic Process White Fat Cell Differentiation Viral Genome Replication Regulation Of DNA-templated Transcription NAD Binding DNA-binding Transcription Factor Binding Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Regulation Of RNA Metabolic Process Transcription Corepressor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Transcription Repressor Complex Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Negative Regulation Of RNA Biosynthetic Process Homomeric SMAD Protein Complex Negative Regulation Of RNA Metabolic Process Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Ubiquitin Protein Ligase Activity Cytosolic Ribosome RQC-trigger Complex GABA-ergic Synapse Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Ligase Complex
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