ELAC2 and DRC3

		ELAC2	DRC3
Description		elaC ribonuclease Z 2	dynein regulatory complex subunit 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid	Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	RNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity TRNA-specific Ribonuclease Activity Hydrolase Activity 3'-tRNA Processing Endoribonuclease Activity Metal Ion Binding	Protein Binding
	Biological Process	TRNA Processing TRNA Decay TRNA 3'-end Processing Mitochondrial TRNA Processing Mitochondrial TRNA 3'-end Processing
Pathways		tRNA processing in the nucleus tRNA processing in the mitochondrion rRNA processing in the mitochondrion tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis
Drugs
Diseases
GWAS		Squamous cell lung carcinoma ( 28604730)
Interacting Genes		12 interacting genes: ASCC2 CTBP1 CTBP2 CUX1 DRC3 GID4 GOLM1 NDUFA7 RING1 RNF10 SMAD2 SUMO2	12 interacting genes: EIF3E ELAC2 FUNDC2 GID4 MFHAS1 PLAGL1 SMCR8 SOD2 SPECC1 ZNF250 ZNF287 ZNF624
Entrez ID		60528	83450
HPRD ID		05641	13181
Ensembl ID		ENSG00000006744	ENSG00000171962
Uniprot IDs		A0A0S2Z5M8 Q9BQ52	B3KSC6 Q9H069
PDB IDs		8CBL 8RR1 8RR3 8RR4 8Z0P 8Z1F 8Z1G 9EY0 9EY1 9EY2	8J07
Enriched GO Terms of Interacting Partners?		Ribosome-associated Ubiquitin-dependent Protein Catabolic Process White Fat Cell Differentiation Viral Genome Replication Regulation Of DNA-templated Transcription NAD Binding DNA-binding Transcription Factor Binding Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Regulation Of RNA Metabolic Process Transcription Corepressor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Transcription Repressor Complex Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Negative Regulation Of RNA Biosynthetic Process Homomeric SMAD Protein Complex Negative Regulation Of RNA Metabolic Process Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Ubiquitin Protein Ligase Activity Cytosolic Ribosome RQC-trigger Complex GABA-ergic Synapse Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Ligase Complex
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