BAP1 and LINC00598

Number of citations of the paper that reports this interaction (PubMedID 28339037)
0

Data Source:
BioGRID (unspecified method, unspecified method)

		BAP1	LINC00598
Description		BRCA1 associated deubiquitinase 1	long intergenic non-protein coding RNA 598
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol PR-DUB Complex
	Molecular Function	Chromatin Binding Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Chromatin DNA Binding Histone H2A Deubiquitinase Activity
	Biological Process	Mitotic Cell Cycle Regulation Of Cell Growth In Utero Embryonic Development Tissue Homeostasis Thrombocyte Differentiation Chromatin Organization Proteolysis Ubiquitin-dependent Protein Catabolic Process Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Gene Expression Regulation Of Gene Expression Protein Deubiquitination Cell Differentiation Erythrocyte Differentiation Neutrophil Differentiation Granulocyte Differentiation Heterochromatin Formation Myeloid Cell Apoptotic Process Monoubiquitinated Protein Deubiquitination Common Myeloid Progenitor Cell Proliferation Protein Modification Process Platelet Morphogenesis Erythrocyte Maturation Nucleate Erythrocyte Differentiation Negative Regulation Of DNA-templated Transcription Regulation Of Inflammatory Response Regulation Of Cell Cycle Hematopoietic Stem Cell Homeostasis Macrophage Homeostasis Neuron Cellular Homeostasis Leukocyte Proliferation Protein K48-linked Deubiquitination Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872)	Asthma ( 31959851) Body mass index (change over time) in chronic obstructive pulmonary disease ( 28044437) Intraocular pressure ( 29617998) Monocyte count ( 29403010)
Interacting Genes		32 interacting genes: ASXL1 BAG4 BCAR3 BRCA1 CASP8 CBLC CBX5 ESR1 H2AC18 H2AC20 H2AC4 H2BC3 HIF1A IGF1R ITPR3 LINC00598 MAP3K1 NBN PARP3 PLN PTPRJ RB1CC1 STK11 TRIM63 UBC UBE2O USP15 USP2 USP21 USP28 XRCC3 YY1	1 interacting genes: BAP1
Entrez ID		8314	646982
HPRD ID		04366
Ensembl ID		ENSG00000163930	ENSG00000215483
Uniprot IDs		F8W6N3 Q92560
PDB IDs		7VPW 8H1T 8SVF
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling Chromatin Organization Protein Modification Process Post-translational Protein Modification Regulation Of Intracellular Signal Transduction Nucleus Protein Metabolic Process Telomere Maintenance Via Telomere Trimming Nuclear Body Cysteine-type Peptidase Activity Heterochromatin Formation Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Nucleoplasm Epigenetic Regulation Of Gene Expression Macromolecule Metabolic Process Response To Radiation Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Signal Transduction Ubiquitin Protein Ligase Binding Negative Regulation Of MiRNA Transcription Structural Constituent Of Chromatin Cysteine-type Deubiquitinase Activity Apoptotic Signaling Pathway Response To Light Stimulus Chromosome Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Protein Deubiquitination Regulation Of Cell Communication Regulation Of Signaling Telomere Maintenance Negative Regulation Of Metabolic Process BRCA1-C Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Localization To Chromosome Negative Regulation Of Growth Double-strand Break Repair Protein Modification By Small Protein Removal Nucleosome DNA Damage Response Telomere Organization Ubiquitin-modified Histone Reader Activity Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA Repair Recombinational Repair Negative Regulation Of Gene Expression Positive Regulation Of Intracellular Signal Transduction	Nucleate Erythrocyte Differentiation Thrombocyte Differentiation Macrophage Homeostasis Platelet Morphogenesis PR-DUB Complex Common Myeloid Progenitor Cell Proliferation Histone H2A Deubiquitinase Activity Monoubiquitinated Protein Deubiquitination Neutrophil Differentiation Myeloid Cell Apoptotic Process Erythrocyte Maturation Granulocyte Differentiation Hematopoietic Stem Cell Homeostasis Protein K48-linked Deubiquitination Myeloid Cell Homeostasis Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Regulation Of Protein Targeting To Mitochondrion Neuron Cellular Homeostasis Leukocyte Homeostasis Erythrocyte Differentiation Regulation Of Cytokine Production Involved In Inflammatory Response Chromatin DNA Binding Cysteine-type Deubiquitinase Activity Protein Deubiquitination Protein Modification By Small Protein Removal Leukocyte Proliferation Cysteine-type Peptidase Activity Heterochromatin Formation Mitotic Cell Cycle Myeloid Leukocyte Differentiation Cell Maturation Anatomical Structure Homeostasis Tissue Homeostasis Negative Regulation Of Gene Expression, Epigenetic Cell Morphogenesis Homeostasis Of Number Of Cells Developmental Maturation Myeloid Cell Differentiation Chordate Embryonic Development In Utero Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Epigenetic Regulation Of Gene Expression Gene Expression
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