GKAP1 and PHOSPHO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GKAP1	PHOSPHO2
Description		G kinase anchoring protein 1	phosphatase, orphan 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Hydrolase Activity Phosphatase Activity Pyridoxal Phosphatase Activity Metal Ion Binding
	Biological Process	Signal Transduction CGMP-mediated Signaling Positive Regulation Of Insulin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Chronotype ( 30696823) Daytime nap ( 33568662) Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Triglyceride levels ( 32154731)	Common carotid intima-media thickness in HIV infection ( 29206233)
Interacting Genes		23 interacting genes: AP3B1 C1orf35 DHFR FAM124B FXR2 HDDC3 HGS HSD11B1 KANK2 KAT5 L3MBTL2 MFAP1 NDN PHOSPHO2 PRKG1 RCOR3 SDCBP SH3BP4 SOX18 TLE1 UBQLN1 UBQLN4 ZCCHC10	7 interacting genes: ATP5PF C1QTNF2 FLNA GKAP1 NAB2 TSEN15 WASHC3
Entrez ID		80318	493911
HPRD ID		17042	17848
Ensembl ID		ENSG00000165113	ENSG00000144362
Uniprot IDs		Q5VSY0	Q8TCD6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Vacuole Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Localization To Lysosome Establishment Of Protein Localization To Vacuole Protein Targeting To Vacuole Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Targeting Positive Regulation Of Exosomal Secretion Aggrephagy Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Circadian Rhythm Regulation Of Exosomal Secretion Transcription Regulator Complex Epithelium Development Autophagy Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Metabolic Process Respiratory System Process Protein Targeting To Lysosome NADP Binding Response To Methotrexate Cortisol Dehydrogenase (NADP+) Activity 11-beta-hydroxysteroid Dehydrogenase (NADP+) Activity 7-beta-hydroxysteroid Dehydrogenase (NADP+) Activity Interleukin-5 Receptor Complex Vacuolar Transport Macroautophagy Histone H2AK5 Acetyltransferase Activity Regulation Of Autophagy Negative Regulation Of Double-strand Break Repair Negative Regulation Of Store-operated Calcium Channel Activity Polyubiquitin Modification-dependent Protein Binding Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Negative Regulation Of DNA Repair
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