PLPPR3 and STRN4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PLPPR3	STRN4
Description		phospholipid phosphatase related 3	striatin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Dendrite Protein-containing Complex Neuronal Cell Body Dendritic Spine FAR/SIN/STRIPAK Complex Postsynapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Phosphatidate Phosphatase Activity	Protein Binding Calmodulin Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Phospholipid Metabolic Process Signal Transduction Phospholipid Dephosphorylation	Negative Regulation Of Hippo Signaling Regulation Of Modification Of Postsynaptic Structure
Pathways		Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Heel bone mineral density ( 28869591 30598549)	Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Primary sclerosing cholangitis ( 23603763)
Interacting Genes		4 interacting genes: ACKR5 BAG6 DRD2 STRN4	28 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 TNIK WIPI2 WNT7A
Entrez ID		79948	29888
HPRD ID		07755	18125
Ensembl ID		ENSG00000129951	ENSG00000090372
Uniprot IDs		Q6T4P5	F5GYK2 Q59GV6 Q9NRL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Synaptic Transmission, Glutamatergic Protein-containing Complex Binding Response To Histamine Regulation Of Synapse Structural Plasticity Dopamine Binding Regulation Of Renal Sodium Excretion Dopamine Neurotransmitter Receptor Activity Regulation Of Synapse Organization Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Catecholamine Uptake Dopamine Uptake Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adenohypophysis Development Negative Regulation Of Dephosphorylation Response To Inactivity Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Migration Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Neuron-neuron Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Peristalsis GABA-ergic Synapse Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Regulation Of Locomotion Involved In Locomotory Behavior Positive Regulation Of Urine Volume Behavioral Response To Ethanol Negative Regulation Of Dopamine Receptor Signaling Pathway Dendritic Spine Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Drinking Behavior Internal Protein Amino Acid Acetylation Internal Peptidyl-lysine Acetylation Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Maintenance Of Unfolded Protein Protein Carrier Chaperone	MAP Kinase Kinase Kinase Kinase Activity MAPK Cascade Regulation Of MAPK Cascade JNK Cascade Regulation Of JNK Cascade Intracellular Signaling Cassette Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Kinase Activity Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Transforming Growth Factor Beta Stimulus Nucleotide Binding ATP Binding Response To Transforming Growth Factor Beta Protein Serine Kinase Activity Protein Phosphorylation Signal Transduction Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Phosphorylation Cytokine Activity Regulation Of Fibroblast Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Junction Assembly Regulation Of Intracellular Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential
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