SON and KCNJ15

		SON	KCNJ15
Description		SON DNA and RNA binding protein	potassium inwardly rectifying channel subfamily J member 15
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck	Plasma Membrane Membrane Monoatomic Ion Channel Complex
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding	Inward Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cytokinesis MRNA Processing RNA Splicing Negative Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cell Cycle	Monoatomic Ion Transport Potassium Ion Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Ritodrine Yohimbine Butamben
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847) Psoriasis ( 25854761)	A body shape index ( 34021172) Appendicular lean mass ( 33097823) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Metabolite levels ( 23823483) Monocyte count ( 32888494) Non-response to antidepressants and depression ( 27622933) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		11 interacting genes: CLIP4 KCNJ15 MAGEA6 PEA15 PRPF40A RCAN1 SNIP1 TRIP6 VHL YWHAB YWHAG	16 interacting genes: CBR3 CTSE DSCAM IL16 KCNE1 KCNJ16 KCNJ2 KCNJ5 LRP8 MTCH1 PATJ SLC39A2 SNTA1 SON TOR1B TTC3
Entrez ID		6651	3772
HPRD ID		01678	03659
Ensembl ID		ENSG00000159140	ENSG00000157551
Uniprot IDs		J3QSZ5 P18583 Q6ZRV7	Q99712
PDB IDs		7CIQ 7CIR 7CIS 7DYN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Phosphatase Inhibitor Activity Protein Sequestering Activity	Regulation Of Monoatomic Ion Transport Membrane Repolarization During Action Potential Membrane Repolarization During Cardiac Muscle Cell Action Potential Voltage-gated Potassium Channel Complex Inward Rectifier Potassium Channel Activity Membrane Repolarization Regulation Of Heart Rate Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Membrane Repolarization Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Cardiac Muscle Cell Action Potential Involved In Contraction Monoatomic Ion Channel Complex Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Potassium Ion Import Across Plasma Membrane Potassium Ion Transmembrane Transport Cardiac Conduction Potassium Ion Transport Regulation Of Heart Contraction Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Blood Circulation Inorganic Cation Import Across Plasma Membrane Ventricular Cardiac Muscle Cell Action Potential Action Potential Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Metal Ion Transport Positive Regulation Of Potassium Ion Transmembrane Transport Inorganic Ion Transmembrane Transport Import Across Plasma Membrane Positive Regulation Of Potassium Ion Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Kinesin Binding Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Ammon Gyrus Development Dendrite Morphogenesis Monoatomic Ion Transport Regulation Of System Process Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Regulation Of Potassium Ion Transmembrane Transport Vestibular Nucleus Development Regulation Of Monoatomic Cation Transmembrane Transport Relaxation Of Skeletal Muscle
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