AKIRIN1 and SNIP1

		AKIRIN1	SNIP1
Description		akirin 1	Smad nuclear interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Membrane	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Cytosol U2-type Precatalytic Spliceosome
	Molecular Function	Transcription Coregulator Activity Protein Binding	RNA Binding MRNA Binding Protein Binding Transcription Regulator Inhibitor Activity
	Biological Process	Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Macrophage Chemotaxis Myoblast Migration Involved In Skeletal Muscle Regeneration Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation Negative Regulation Of Satellite Cell Differentiation	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing MiRNA Processing Negative Regulation Of Canonical NF-kappaB Signal Transduction U2-type Prespliceosome Assembly
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Beard thickness ( 26926045)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		4 interacting genes: GOPC MAP7D1 SNIP1 USP7	57 interacting genes: AKIRIN1 CDK6 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG EVA1B FAF1 GMEB1 GYS1 HIPK1 HIPK3 JUN KRTAP10-6 MAX MYC NFATC2 OXSM PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 POU3F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SH3D21 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM2 SRRM4 STK3 STK40 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451 ZNF496
Entrez ID		79647	79753
HPRD ID		07787	06999
Ensembl ID		ENSG00000174574	ENSG00000163877
Uniprot IDs		Q9H9L7	B1AK66 Q8TAD8
PDB IDs			5Z56 5Z57 5Z58 6FF7 7ABG 7ABH 7ABI 7DVQ 8I0P 8I0R
Enriched GO Terms of Interacting Partners?		Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Anion Channel Activity Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Monoubiquitinated Protein Deubiquitination DNA Alkylation Repair Regulation Of Telomere Capping Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Protein Localization To Cell Surface Regulation Of Monoatomic Anion Transport Golgi-associated Vesicle Membrane Apical Protein Localization Molecular Sequestering Activity Trans-Golgi Network Transport Vesicle K48-linked Deubiquitinase Activity Negative Regulation Of Gluconeogenesis	Regulation Of Nucleobase-containing Compound Metabolic Process PML Body Chromatin Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process SUMO Transferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Sumoylation SUMO Ligase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Binding Nuclear Speck DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Metabolic Process Regulation Of MiRNA Metabolic Process Nucleobase-containing Compound Metabolic Process
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