C1orf50 and APPBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		C1orf50	APPBP2
Description		chromosome 1 open reading frame 50	amyloid beta precursor protein binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Membrane Cytoplasmic Vesicle Membrane Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Identical Protein Binding	Microtubule Motor Activity Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Biological_process	Intracellular Protein Transport Protein Transport Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intracellular Transport
Pathways
Drugs
Diseases
GWAS			Interleukin-6 levels ( 33517400) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)
Interacting Genes		18 interacting genes: ADCY4 AHCY APPBP2 CLSPN CRX EIF2B1 EPM2AIP1 EXO5 INCA1 LRP2BP MEOX1 MEOX2 NTAQ1 PPCS REL TCF4 UBC ZMYND12	122 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ASCC3 ATP13A1 BCL7A BIN2 C1orf50 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MGAT4B MLLT3 MMP28 MRPL28 MSH2 MSLN MUL1 MYLK NFYA NHERF1 NPRL3 PCSK5 PEX39 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC33A2 SLC7A10 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		79078	10513
HPRD ID		14714	05616
Ensembl ID		ENSG00000164008	ENSG00000062725
Uniprot IDs		Q9BV19	Q92624
PDB IDs			8JAL 8JAQ 8JAR 8JAS 8JAU 8JAV
Enriched GO Terms of Interacting Partners?		Somite Specification DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Segment Specification Somite Development Nucleus DNA-binding Transcription Factor Activity	Protein Binding
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