APPBP2 and WNT5B

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APPBP2	WNT5B
Description		amyloid beta precursor protein binding protein 2	Wnt family member 5B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Membrane Cytoplasmic Vesicle Membrane Cul2-RING Ubiquitin Ligase Complex	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface Endocytic Vesicle Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Signaling Receptor Binding Frizzled Binding Cytokine Activity
	Biological Process	Intracellular Protein Transport Protein Transport Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intracellular Transport	Chondrocyte Differentiation Wnt Signaling Pathway Neuron Differentiation Positive Regulation Of Cell Migration Muscle Cell Differentiation Cell Fate Commitment Fat Cell Differentiation Positive Regulation Of Fat Cell Differentiation Canonical Wnt Signaling Pathway Lens Fiber Cell Development Cellular Response To Retinoic Acid Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Convergent Extension Involved In Gastrulation Positive Regulation Of Non-canonical Wnt Signaling Pathway
Pathways			WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking PCP/CE pathway PCP/CE pathway
Drugs
Diseases
GWAS		Interleukin-6 levels ( 33517400) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gout ( 22179738) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		122 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ASCC3 ATP13A1 BCL7A BIN2 C1orf50 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MGAT4B MLLT3 MMP28 MRPL28 MSH2 MSLN MUL1 MYLK NFYA NHERF1 NPRL3 PCSK5 PEX39 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC33A2 SLC7A10 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747	2 interacting genes: APPBP2 PORCN
Entrez ID		10513	81029
HPRD ID		05616	05899
Ensembl ID		ENSG00000062725	ENSG00000111186
Uniprot IDs		Q92624	Q9H1J7
PDB IDs		8JAL 8JAQ 8JAR 8JAS 8JAU 8JAV
Enriched GO Terms of Interacting Partners?		Protein Binding	Palmitoleoyltransferase Activity Protein Palmitoleylation Wnt Protein Secretion Cul2-RING Ubiquitin Ligase Complex Protein Lipidation Wnt-protein Binding AMPA Glutamate Receptor Complex Microtubule Associated Complex Protein Transport Establishment Of Protein Localization Microtubule Motor Activity Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein Modification Process Intracellular Protein Localization Ubiquitin-like Ligase-substrate Adaptor Activity
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