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YY1 and CREB1
Number of citations of the paper that reports this interaction (PubMedID
7769693
)
36
Data Source:
BioGRID
(two hybrid)
YY1
CREB1
Description
YY1 transcription factor
cAMP responsive element binding protein 1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Chromatin Silencing Complex
Nuclear Matrix
Ino80 Complex
PcG Protein Complex
Chromatin
Euchromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Mitochondrial Matrix
Centrosome
Cytosol
Axon
Ciliary Basal Body
RNA Polymerase II Transcription Regulator Complex
ATF4-CREB1 Transcription Factor Complex
Molecular Function
Four-way Junction DNA Binding
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
RNA Binding
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
SMAD Binding
Metal Ion Binding
DNA-binding Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Transcription Cis-regulatory Region Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coactivator Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Double-stranded DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Enzyme Binding
Hsp70 Protein Binding
Histone Acetyltransferase Binding
CAMP Response Element Binding
Identical Protein Binding
Sequence-specific DNA Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Arrestin Family Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
Regulation Of DNA Replication
DNA Repair
Regulation Of DNA Repair
DNA Recombination
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
RNA Localization
DNA Damage Response
Spermatogenesis
Anterior/posterior Pattern Specification
Response To UV-C
Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Hemopoiesis
Cell Differentiation
B Cell Differentiation
Negative Regulation Of Interferon-beta Production
Regulation Of Chromosome Organization
Cellular Response To UV
Response To Prostaglandin F
Positive Regulation Of DNA Repair
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Camera-type Eye Morphogenesis
Chromosome Organization
Regulation Of Cell Cycle
Regulation Of DNA Strand Elongation
Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Cellular Response To Interleukin-1
Immunoglobulin Heavy Chain V-D-J Recombination
Negative Regulation Of MiRNA Transcription
Positive Regulation Of Telomere Maintenance In Response To DNA Damage
Response To Hypoxia
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Protein Phosphorylation
Signal Transduction
Transforming Growth Factor Beta Receptor Signaling Pathway
Axonogenesis
Lactation
Memory
Circadian Rhythm
Regulation Of Cell Size
Visual Learning
Response To Xenobiotic Stimulus
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription By Competitive Promoter Binding
Response To Purine-containing Compound
Response To Activity
Pituitary Gland Development
Cell Differentiation
Osteoclast Differentiation
Mammary Gland Development
Positive Regulation Of Transforming Growth Factor Beta3 Production
Secretory Granule Organization
Response To Glucagon
Chemotaxis To Arachidonate
Response To Nicotine
Cellular Response To Hepatocyte Growth Factor Stimulus
Response To Erythropoietin
Cellular Response To Platelet-derived Growth Factor Stimulus
Positive Regulation Of Multicellular Organism Growth
Response To Cocaine
MRNA Transcription By RNA Polymerase II
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Response To Morphine
Response To Ethanol
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoclast Differentiation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Hormone Secretion
Positive Regulation Of Hormone Secretion
Positive Regulation Of Lipid Biosynthetic Process
Regulation Of Fibroblast Proliferation
Rhythmic Process
Protein Stabilization
Positive Regulation Of Cardiac Muscle Tissue Development
Regulation Of Glial Cell Proliferation
Lung Epithelium Development
Lung Saccule Development
Type I Pneumocyte Differentiation
Cellular Response To Zinc Ion
Cellular Response To Retinoic Acid
Cellular Response To Growth Factor Stimulus
Cellular Response To Fatty Acid
Cellular Response To Transforming Growth Factor Beta Stimulus
CAMP/PKA Signal Transduction
Positive Regulation Of Long-term Synaptic Potentiation
Response To L-glutamate
Response To Dehydroepiandrosterone
Positive Regulation Of Membrane Depolarization
Cellular Response To Forskolin
Cellular Response To Nerve Growth Factor Stimulus
Cellular Response To Insulin-like Growth Factor Stimulus
Cellular Response To Leukemia Inhibitory Factor
Response To Hypobaric Hypoxia
Regulation Of Testosterone Biosynthetic Process
Pathways
Activation of anterior HOX genes in hindbrain development during early embryogenesis
UCH proteinases
DNA Damage Recognition in GG-NER
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Estrogen-dependent gene expression
Drugs
Adenosine phosphate
Naloxone
Diseases
GWAS
Estimated glomerular filtration rate (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Pulse pressure (
30224653
)
Body mass index (
25673413
28892062
)
Diastolic blood pressure (
27841878
)
Food antigen IgG levels (
24962563
)
Mean corpuscular hemoglobin (
32888494
)
Refractive error (
32231278
)
Systolic blood pressure (
27841878
)
Interacting Genes
99 interacting genes:
ALOXE3
APP
ATF2
ATF6
ATF7
AURKA
BAP1
BRCA1
CDKN2A
CEBPA
CEP76
CREB1
CREBBP
CRKL
CYSRT1
DNMT3L
E2F2
E2F3
EED
EP300
ESM1
FHL2
FKBP1A
FKBP3
FOXP1
FOXP2
FOXP4
GFER
GMCL1
GRN
GTF2I
HDAC2
HDAC3
HMGB1
HNF1B
HOXA11
IL10
ITCH
KAT2B
KRTAP1-3
KRTAP1-5
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-3
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP4-2
KRTAP4-5
KRTAP5-6
KRTAP9-3
KRTAP9-8
MDFI
MED20
MTA2
MYC
NEDD4L
NFIC
NFIX
NFKB1
NOTCH1
NPM1
NR1H2
PIAS4
PLEKHF2
PPIA
PRKD1
PSMD9
RAF1
RYBP
SAP30
SF3A2
SKP2
SLC39A7
SMAD1
SMAD2
SMAD3
SMURF2
SP1
SPRY1
SREBF1
TESK1
TFCP2
TP53
TRIM42
TWIST1
UBE2I
UHRF2
USP21
USP7
VWC2
XAGE1A
XAGE1B
YAF2
ZNF232
ZNF85
ZRANB2
87 interacting genes:
ABL1
AGR2
AKT1
ATF1
ATF6
ATF7IP
ATM
ATR
BRD10
CAMK2A
CCDC6
CD274
CDK1
CEBPB
CHD3
CHD8
CREBBP
CREM
CRTC1
CRTC2
CSNK1D
CSNK2A1
CSNK2B
DNMT3L
DYRK1A
EDF1
ERG28
ETS1
FHL5
GLI2
GSK3A
GSK3B
GTF2A1
GTF2F2
HIPK3
HIVEP1
HNF1B
HPS6
KAT5
KCNIP3
MAPK14
MAPKAPK2
MTF2
NR3C1
PDX1
PIAS1
PIAS2
POGZ
POU2F1
PPP1CA
PRKACA
PRKG1
PTEN
RAB1A
RBBP4
RECQL5
RFX3
RGS13
RNF111
RNF4
RPS6KA1
RPS6KA2
RPS6KA3
RPS6KA4
RPS6KA5
SGK1
SMARCA4
SMARCA5
SMCO1
SOX9
SRA1
SREBF2
SRF
SUZ12
THRA
TOX4
TRIM22
TSSK4
UBE2I
VIM
YY1
ZHX1
ZMYM2
ZNF35
ZNF436
ZNF451
ZNF92
Entrez ID
7528
1385
HPRD ID
02482
00442
Ensembl ID
ENSG00000100811
ENSG00000118260
Uniprot IDs
P25490
B7Z5C6
P16220
Q53X93
Q5U0J5
PDB IDs
1UBD
1ZNM
4C5I
2LXT
5ZK1
5ZKO
7TBH
Enriched GO Terms of Interacting Partners
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Negative Regulation Of RNA Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Regulation Of Primary Metabolic Process
Nucleoplasm
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Metabolic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Intermediate Filament
Chromatin
Regulation Of Macromolecule Biosynthetic Process
DNA-binding Transcription Factor Activity
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Keratin Filament
Epigenetic Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-templated Transcription
DNA Binding
Cis-regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Biosynthetic Process
Transcription Coregulator Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Regulation Of Metabolic Process
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription By RNA Polymerase II
Negative Regulation Of Gene Expression
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Binding
Identical Protein Binding
Regulation Of MiRNA Metabolic Process
Regulation Of Programmed Cell Death
Transcription Regulator Complex
Chromatin Remodeling
Regulation Of Primary Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of RNA Metabolic Process
Nucleoplasm
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Protein Serine/threonine Kinase Activity
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Serine Kinase Activity
Protein Kinase Activity
PML Body
Kinase Activity
Chromatin
DNA Binding
Negative Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
ATP Binding
Transferase Activity
Chromatin Remodeling
Phosphorylation
Cellular Response To Oxygen-containing Compound
Cellular Response To Stress
Positive Regulation Of CREB Transcription Factor Activity
DNA-binding Transcription Factor Activity
Chromatin Organization
Sequence-specific DNA Binding
Nucleic Acid Metabolic Process
Intracellular Signal Transduction
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