SMIM5 and PRRT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMIM5	PRRT2
Description		small integral membrane protein 5	proline rich transmembrane protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Synaptic Vesicle Membrane Axon Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Presynaptic Membrane Cell Projection Dendritic Spine Axon Terminus Synapse Postsynaptic Membrane Presynapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Syntaxin-1 Binding
	Biological Process		Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Negative Regulation Of Short-term Synaptic Potentiation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: ARFIP1 EHHADH PRRT2 RBFA SGTA SH3GLB1 ZFYVE21	13 interacting genes: AQP6 CFAP119 F2RL1 GPRC5D KAT8 ORAI3 SLC10A6 SLC71A2 SMIM5 SNAP25 TLCD4 TMEM219 ZNF689
Entrez ID		643008	112476
HPRD ID			13995
Ensembl ID		ENSG00000204323	ENSG00000167371
Uniprot IDs		Q71RC9	Q7Z6L0
PDB IDs
Enriched GO Terms of Interacting Partners?		Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds TRC Complex Negative Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Vacuolar Membrane Negative Regulation Of Short-term Synaptic Potentiation Negative Regulation Of SNARE Complex Assembly Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Delta(3)-delta(2)-enoyl-CoA Isomerase Activity BAT3 Complex Binding 'de Novo' Post-translational Protein Folding Positive Regulation Of Membrane Tubulation Negative Regulation Of Vesicle Fusion Autophagic Cell Death Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Negative Regulation Of ERAD Pathway Regulation Of Retrograde Transport, Endosome To Golgi Phosphatidylinositol 3-kinase Activator Activity 3-hydroxyacyl-CoA Dehydratase Activity
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