TFB2M and TFAM

Number of citations of the paper that reports this interaction (PubMedID 12068295)
0

Data Source:
HPRD (in vitro)

		TFB2M	TFAM
Description		transcription factor B2, mitochondrial	transcription factor A, mitochondrial
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Protein-containing Complex Mitochondrial Nucleoid
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity RNA Binding Methyltransferase Activity RRNA (adenine-N6-)-methyltransferase Activity Transferase Activity Mitochondrial Transcription Factor Activity	Mitochondrial Promoter Sequence-specific DNA Binding Transcription Coactivator Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Heat Shock Protein Binding Mitochondrial Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	RRNA Modification RRNA Processing Mitochondrial Transcription Transcription Initiation At Mitochondrial Promoter RRNA Methylation Methylation	Response To Hypoxia Mitochondrial Transcription Transcription Initiation At Mitochondrial Promoter Response To Nutrient Mitochondrial Respiratory Chain Complex Assembly
Pathways		Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis	Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) hemolysis of donated blood (osmotic) ( 34014839) Metabolite levels ( 23823483)	Blood urea nitrogen levels ( 29403010) Height ( 23456168) Metabolite levels ( 23823483) Midgestational circulating levels of PCBs ( 28235828) Mitochondrial heteroplasmy measurement ( 33731350) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: MUC1 PNP POLRMT TFAM	10 interacting genes: AGTRAP ARL6IP1 COL8A2 MGST3 PNP STATH TECR TFB1M TFB2M TSPAN1
Entrez ID		64216	7019
HPRD ID		09520	02702
Ensembl ID		ENSG00000162851	ENSG00000108064
Uniprot IDs		Q9H5Q4	E5KSU5 Q00059
PDB IDs		6ERO 6ERP 6ERQ	3FGH 3TMM 3TQ6 4NNU 4NOD 6ERP 6ERQ 6HB4 6HC3 7LBW 7LBX
Enriched GO Terms of Interacting Partners?		Mitochondrial Promoter Sequence-specific DNA Binding Transcription Initiation At Mitochondrial Promoter Mitochondrial Transcription Mitochondrial Nucleoid Mitochondrial RNA Metabolic Process DNA-templated Transcription Initiation Purine-nucleoside Phosphorylase Activity Purine Nucleobase Binding Urate Biosynthetic Process Nicotinamide Riboside Catabolic Process Guanosine Phosphorylase Activity Inosine Catabolic Process Deoxyinosine Catabolic Process Mitochondrial DNA-directed RNA Polymerase Complex Nucleobase-containing Compound Biosynthetic Process Nucleoside Binding Deoxyadenosine Catabolic Process DAMP Catabolic Process Mitochondrial Transcription Factor Activity Purine Ribonucleoside Catabolic Process Purine Deoxyribonucleoside Metabolic Process IMP Catabolic Process Deoxyribonucleoside Catabolic Process Pentosyltransferase Activity Purine Ribonucleoside Salvage Purine Nucleoside Catabolic Process 5'-3' RNA Polymerase Activity Allantoin Metabolic Process Urate Metabolic Process Negative Regulation Of Cell Adhesion Mediated By Integrin Phosphate Ion Binding Nucleoside Salvage Purine Nucleoside Monophosphate Catabolic Process Mitochondrial DNA Replication Negative Regulation Of Transcription By Competitive Promoter Binding Nucleobase-containing Small Molecule Catabolic Process Deoxyribonucleoside Monophosphate Catabolic Process Mitochondrial Matrix Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitotic G1 DNA Damage Checkpoint Signaling DNA-templated Transcription Mitotic G1/S Transition Checkpoint Signaling IMP Metabolic Process Sequence-specific DNA Binding Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitochondrial DNA Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Purine Nucleoside Metabolic Process Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process	RRNA (adenine-N6,N6-)-dimethyltransferase Activity Mitochondrial Transcription Factor Activity Transcription Initiation At Mitochondrial Promoter RRNA Methylation RRNA Modification Mitochondrial RNA Metabolic Process Mitochondrial Nucleoid Collagen Type VIII Trimer Purine-nucleoside Phosphorylase Activity Purine Nucleobase Binding Urate Biosynthetic Process Nicotinamide Riboside Catabolic Process Nucleobase-containing Compound Biosynthetic Process Guanosine Phosphorylase Activity Inosine Catabolic Process Deoxyinosine Catabolic Process Extracellular Matrix Constituent, Lubricant Activity Very-long-chain Enoyl-CoA Reductase Activity DNA-templated Transcription Initiation RNA Methylation Small Molecule Biosynthetic Process Endoplasmic Reticulum Membrane Nucleoside Binding DAMP Catabolic Process Deoxyadenosine Catabolic Process Structural Constituent Of Tooth Enamel Hydroxyapatite Binding Very-long-chain Fatty Acyl-CoA Dehydrogenase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Macromolecule Methylation Angiotensin Type II Receptor Activity RRNA (adenine-N6-)-methyltransferase Activity Leukotriene-C4 Synthase Activity Purine Ribonucleoside Catabolic Process Purine Deoxyribonucleoside Metabolic Process IMP Catabolic Process Regulation Of Endoplasmic Reticulum Tubular Network Organization Deoxyribonucleoside Catabolic Process Pentosyltransferase Activity Saliva Secretion Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Formation RNA Modification Purine Ribonucleoside Salvage Purine Nucleoside Catabolic Process Methyltransferase Activity Allantoin Metabolic Process Endoplasmic Reticulum Tubular Network Membrane Organization Mitochondrial Transcription Urate Metabolic Process
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