RBBP7 and BRMS1L

Number of citations of the paper that reports this interaction (PubMedID 15451426)
0

Data Source:
HPRD (in vivo)

		RBBP7	BRMS1L
Description		RB binding protein 7, chromatin remodeling factor	BRMS1 like transcriptional repressor
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol NuRD Complex NURF Complex ESC/E(Z) Complex Sin3-type Complex ATPase Complex	Nucleus Nucleoplasm Sin3-type Complex
	Molecular Function	RNA Binding Protein Binding Histone Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Brain Development Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Fate Specification Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Response To Steroid Hormone Cellular Heat Acclimation Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways		PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS Defective pyroptosis Negative Regulation of CDH1 Gene Transcription Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		32 interacting genes: APPL1 APPL2 BRCA1 BRMS1 BRMS1L BUB3 CREBBP CRYAA CYTOR DDB1 DHX30 ERCC6 ESR1 H3-4 H3C1 H4C1 HDAC1 HDAC2 ING1 MBD3 MTA2 NR2E3 PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1	22 interacting genes: ACTN2 AMOTL2 BRMS1 CEP70 CYTOR DEUP1 EXOC5 HDAC1 HDAC2 ING1 MCRS1 MID2 PBX1 PBX2 RBBP4 RBBP7 RBP1 SAP30 SIN3A TEX11 TULP3 TXLNA
Entrez ID		5931	84312
HPRD ID		04231	16564
Ensembl ID		ENSG00000102054	ENSG00000100916
Uniprot IDs		Q16576 Q6FHQ0	Q5PSV4
PDB IDs		3CFS 3CFV 7M3X
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Chromatin Remodeling Chromatin Organization Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Nucleus Negative Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Epigenetic Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process NuRD Complex Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Histone Deacetylase Complex Regulation Of Gene Expression Negative Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Fate Specification Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Rhythmic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Developmental Process Histone Deacetylase Binding Negative Regulation Of Developmental Process Protein-containing Complex Heterochromatin Formation Negative Regulation Of Signal Transduction Regulation Of Cellular Response To Growth Factor Stimulus Nucleosomal DNA Binding Chromatin Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cell Fate Commitment Negative Regulation Of Gene Expression, Epigenetic Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Migration Regulation Of Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Deacetylase Complex Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway NuRD Complex Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Cell Fate Specification Negative Regulation Of Developmental Process Regulation Of Cell Fate Commitment Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process ESC/E(Z) Complex Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Stem Cell Differentiation Regulation Of Locomotion Regulation Of Nucleobase-containing Compound Metabolic Process Protein Lysine Delactylase Activity Fungiform Papilla Formation Negative Regulation Of Nucleobase-containing Compound Metabolic Process NF-kappaB Binding Protein Decrotonylase Activity Histone Decrotonylase Activity Brain Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Hair Follicle Placode Formation Negative Regulation Of DNA-templated Transcription Nucleosomal DNA Binding Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of RNA Metabolic Process Cellular Response To Dopamine NURF Complex Response To Dopamine Embryonic Digit Morphogenesis Negative Regulation Of Cell Communication
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