BRMS1L and SAP30

Number of citations of the paper that reports this interaction (PubMedID 15451426)
0

Data Source:
HPRD (in vivo)

		BRMS1L	SAP30
Description		BRMS1 like transcriptional repressor	Sin3A associated protein 30
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Sin3-type Complex	Histone Deacetylase Complex Nucleus Nucleoplasm Sin3-type Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Cell Differentiation Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS
Interacting Genes		22 interacting genes: ACTN2 AMOTL2 BRMS1 CEP70 CYTOR DEUP1 EXOC5 HDAC1 HDAC2 ING1 MCRS1 MID2 PBX1 PBX2 RBBP4 RBBP7 RBP1 SAP30 SIN3A TEX11 TULP3 TXLNA	29 interacting genes: BRMS1 BRMS1L CIRSR CYTOR GABBR2 H2AC16 H2BC21 H3-4 H4C16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A UHRF1 VHL YY1 ZNF395
Entrez ID		84312	8819
HPRD ID		16564	04540
Ensembl ID		ENSG00000100916	ENSG00000164105
Uniprot IDs		Q5PSV4	O75446
PDB IDs			2KDP
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Deacetylase Complex Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway NuRD Complex Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Cell Fate Specification Negative Regulation Of Developmental Process Regulation Of Cell Fate Commitment Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process ESC/E(Z) Complex Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Stem Cell Differentiation Regulation Of Locomotion Regulation Of Nucleobase-containing Compound Metabolic Process Protein Lysine Delactylase Activity Fungiform Papilla Formation Negative Regulation Of Nucleobase-containing Compound Metabolic Process NF-kappaB Binding Protein Decrotonylase Activity Histone Decrotonylase Activity Brain Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Hair Follicle Placode Formation Negative Regulation Of DNA-templated Transcription Nucleosomal DNA Binding Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of RNA Metabolic Process Cellular Response To Dopamine NURF Complex Response To Dopamine Embryonic Digit Morphogenesis Negative Regulation Of Cell Communication	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Histone Deacetylase Complex Negative Regulation Of RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleoplasm Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process NuRD Complex Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Metabolic Process Negative Regulation Of Cell Migration Regulation Of Cell Fate Specification Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Developmental Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Fate Commitment Transcription Corepressor Activity Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process ESC/E(Z) Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Androgen Receptor Signaling Pathway Heterochromatin Formation Rhythmic Process Transcription Repressor Complex
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