CIP2A and WWC3

Number of citations of the paper that reports this interaction (PubMedID 34145035)
49

Data Source:
BioGRID (two hybrid)

		CIP2A	WWC3
Description		cellular inhibitor of PP2A	WWC family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome Cytoplasm Centrosome Cytosol Plasma Membrane Ciliary Basal Body	Cytoplasm Cytosol
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding Protein Homodimerization Activity Cadherin Binding	Kinase Binding Signaling Adaptor Activity Molecular Adaptor Activity
	Biological Process	DNA Damage Response Chromosome Organization Broken Chromosome Clustering	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Population Proliferation Cell Migration Hippo Signaling Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Negative Regulation Of Organ Growth
Pathways
Drugs
Diseases
GWAS			Mild influenza (H1N1) infection ( 26379185) Prostate cancer ( 23535732)
Interacting Genes		24 interacting genes: ATIC CDK1 CENPC CEP152 CEP192 CSNK2B CSPP1 GOLGA4 LAMB2 MYC NDC80 NEK2 PIK3R1 PPP2R5C PSMA1 PSMA3 RBM5 RNF2 SMC5 STUB1 SYNCRIP TOPBP1 UBR5 WWC3	5 interacting genes: APP CIP2A WBP2 WWC1 WWC2
Entrez ID		57650	55841
HPRD ID		11151	11136
Ensembl ID		ENSG00000163507	ENSG00000047644
Uniprot IDs		Q8TCG1	Q9ULE0
PDB IDs		5UFL
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromosome Organization Centrosome Chromosome Chromosome, Centromeric Region Centrosome Duplication Procentriole DNA Damage Response Cytosol Positive Regulation Of Chromosome Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Protein Import Into Nucleus Cytoplasm Microtubule Cytoskeleton Organization Involved In Mitosis Procentriole Replication Complex Chromosome Segregation Mitotic Cell Cycle Membraneless Organelle Assembly Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Process Proteasome Core Complex, Alpha-subunit Complex Cell Cycle Phase Transition Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Nuclear Body Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Catabolic Process Microtubule Organizing Center Organization Ubiquitin-ubiquitin Ligase Activity Kinetochore Organization Positive Regulation Of Intracellular Protein Transport Proteolysis Involved In Protein Catabolic Process Mitotic Spindle Organization Spindle Assembly Cell Division Positive Regulation Of Protein Localization To Nucleus Attachment Of Mitotic Spindle Microtubules To Kinetochore Proteasome Core Complex DNA Metabolic Process Protein Localization To Chromosome Intracellular Signal Transduction Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Cell Cycle Process Peptidyl-threonine Phosphorylation Macromolecule Metabolic Process Regulation Of Cell Cycle PML Body	Hippo Signaling Negative Regulation Of Hippo Signaling Negative Regulation Of Organ Growth Regulation Of Developmental Growth Regulation Of Hippo Signaling Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Organ Growth Signaling Adaptor Activity Negative Regulation Of Developmental Growth Kinase Binding Regulation Of Growth Acetylcholine Receptor Activator Activity Negative Regulation Of Cell Population Proliferation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Signal Transduction Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Regulation Of Intracellular Signal Transduction Positive Regulation Of G Protein-coupled Receptor Internalization Broken Chromosome Clustering Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Molecular Adaptor Activity Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Negative Regulation Of Transcription By RNA Polymerase II NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Negative Regulation Of Growth Regulation Of Transcription By RNA Polymerase II
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