AP1AR and AP1G1

Number of citations of the paper that reports this interaction (PubMedID 15775984)
57

Data Source:
HPRD (two hybrid, in vitro)

		AP1AR	AP1G1
Description		adaptor related protein complex 1 associated regulatory protein	adaptor related protein complex 1 subunit gamma 1
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Golgi Apparatus Cytosol Transport Vesicle	Golgi Membrane Cytoplasm Lysosomal Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Clathrin-coated Pit Membrane Membrane Coat AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Synapse Perinuclear Region Of Cytoplasm Recycling Endosome Intracellular Vesicle Presynapse
	Molecular Function	Protein Binding Kinesin Binding AP-1 Adaptor Complex Binding	Protein Binding Collagen Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity
	Biological Process	Negative Regulation Of Receptor Recycling Intracellular Protein Localization Protein Transport Regulation Of Arp2/3 Complex-mediated Actin Nucleation Substrate Adhesion-dependent Cell Spreading Vesicle Targeting, Trans-Golgi To Endosome Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cell Motility	Intracellular Protein Transport Golgi To Vacuole Transport Protein Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Synaptic Vesicle Endocytosis Platelet Dense Granule Organization Golgi To Lysosome Transport Basolateral Protein Secretion Melanosome Assembly
Pathways			Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Body mass index ( 26426971)	General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		3 interacting genes: AP1G1 GGA1 KLC1	31 interacting genes: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 GGA1 GGA2 GGA3 HEATR5B KIF13A MAP1A PLK2 PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 UPF1 ZNF512B
Entrez ID		55435	164
HPRD ID		12824	04637
Ensembl ID		ENSG00000138660	ENSG00000166747
Uniprot IDs		Q63HQ0	A0A140VJE7 O43747 Q8IY97
PDB IDs			1IU1
Enriched GO Terms of Interacting Partners?		Kinesin Binding Post-Golgi Vesicle-mediated Transport Cytosolic Transport Synaptic Vesicle Budding From Endosome Trans-Golgi Network Small GTPase Binding Basolateral Protein Secretion Positive Regulation Of Natural Killer Cell Degranulation Golgi Vesicle Transport Early Endosome Stress Granule Disassembly Protein Localization To Ciliary Membrane Endosome To Melanosome Transport Golgi To Lysosome Transport AP-1 Adaptor Complex Clathrin Adaptor Activity Intracellular Protein Transport Melanosome Assembly Golgi To Vacuole Transport Intracellular Vesicle GTP-dependent Protein Binding Platelet Dense Granule Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Membrane Coat Protein Localization To Cell Surface Positive Regulation Of Natural Killer Cell Mediated Immunity Clathrin-coated Vesicle Membrane Vesicle Budding From Membrane Synaptic Vesicle Endocytosis Melanosome Organization Pigment Granule Organization Golgi To Plasma Membrane Protein Transport Cytoplasmic Vesicle Presynaptic Endocytosis Kinesin Complex Positive Regulation Of Regulated Secretory Pathway Cytoskeletal Motor Activity Regulation Of Natural Killer Cell Mediated Cytotoxicity Establishment Of Protein Localization To Plasma Membrane Regulation Of Natural Killer Cell Mediated Immunity Protein Localization To Cilium Golgi To Plasma Membrane Transport Collagen Binding Protein Transport Positive Regulation Of Leukocyte Mediated Cytotoxicity Secretory Granule Organization Positive Regulation Of Cell Killing Clathrin-coated Pit Clathrin-coated Vesicle Vesicle-mediated Transport	Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Clathrin-coated Vesicle AP-1 Adaptor Complex Intracellular Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Golgi Apparatus Early Endosome Post-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Endocytosis Endosomal Transport Golgi To Plasma Membrane Transport Cytosolic Transport Vesicle-mediated Transport To The Plasma Membrane Golgi To Plasma Membrane Protein Transport Import Into Cell Cytoplasmic Vesicle Golgi Vesicle Transport Trans-Golgi Network Establishment Of Protein Localization To Plasma Membrane Basolateral Protein Secretion Clathrin-coated Pit Clathrin Binding Endosome Melanosome Organization Cytoplasmic Vesicle Membrane Pigment Granule Organization Retrograde Transport, Endosome To Golgi Cytosol Early Endosome Membrane Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Localization Within Membrane Melanosome Assembly Clathrin Adaptor Activity Clathrin Coat Assembly Platelet Dense Granule Organization Receptor-mediated Endocytosis Protein Localization To Membrane Vesicle Organization Membrane Coat Protein Localization To Cell Surface Protein Localization To Plasma Membrane Ubiquitin Binding Phosphatidylinositol Binding
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