AP1G1 and AP1M2

Number of citations of the paper that reports this interaction (PubMedID 10535737)
0

Data Source:
HPRD (in vivo)

		AP1G1	AP1M2
Description		adaptor related protein complex 1 subunit gamma 1	adaptor related protein complex 1 subunit mu 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Clathrin-coated Pit Membrane Membrane Coat AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Synapse Perinuclear Region Of Cytoplasm Recycling Endosome Intracellular Vesicle Presynapse	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Collagen Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity	Protein Binding Clathrin Adaptor Activity
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Protein Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Synaptic Vesicle Endocytosis Platelet Dense Granule Organization Golgi To Lysosome Transport Basolateral Protein Secretion Melanosome Assembly	Protein Targeting Intracellular Protein Transport Vesicle Targeting Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Localization In Cell Basolateral Protein Secretion
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 27863252) Plateletcrit ( 27863252 32888494) Red cell distribution width ( 27863252 28957414 32888494)
Interacting Genes		31 interacting genes: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 GGA1 GGA2 GGA3 HEATR5B KIF13A MAP1A PLK2 PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 UPF1 ZNF512B	21 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH CDK12 ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		164	10053
HPRD ID		04637	06296
Ensembl ID		ENSG00000166747	ENSG00000129354
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	Q53GI5 Q9Y6Q5
PDB IDs		1IU1
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Clathrin-coated Vesicle AP-1 Adaptor Complex Intracellular Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Golgi Apparatus Early Endosome Post-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Endocytosis Endosomal Transport Golgi To Plasma Membrane Transport Cytosolic Transport Vesicle-mediated Transport To The Plasma Membrane Golgi To Plasma Membrane Protein Transport Import Into Cell Cytoplasmic Vesicle Golgi Vesicle Transport Trans-Golgi Network Establishment Of Protein Localization To Plasma Membrane Basolateral Protein Secretion Clathrin-coated Pit Clathrin Binding Endosome Melanosome Organization Cytoplasmic Vesicle Membrane Pigment Granule Organization Retrograde Transport, Endosome To Golgi Cytosol Early Endosome Membrane Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Localization Within Membrane Melanosome Assembly Clathrin Adaptor Activity Clathrin Coat Assembly Platelet Dense Granule Organization Receptor-mediated Endocytosis Protein Localization To Membrane Vesicle Organization Membrane Coat Protein Localization To Cell Surface Protein Localization To Plasma Membrane Ubiquitin Binding Phosphatidylinositol Binding	AP-1 Adaptor Complex Early Endosome Melanosome Assembly Clathrin Adaptor Activity Basolateral Protein Secretion Platelet Dense Granule Organization Clathrin-coated Pit Vesicle-mediated Transport Membrane Coat Melanosome Organization Pigment Granule Organization Trans-Golgi Network Membrane Cytoplasmic Vesicle Clathrin Adaptor Complex Import Into Cell Intracellular Transport Establishment Of Localization In Cell Synaptic Vesicle Endocytosis Secretory Granule Organization Regulation Of Amyloid Fibril Formation GTP-dependent Protein Binding Regulation Of Vesicle-mediated Transport Cellular Localization Lysosomal Membrane Secretion By Cell Presynapse Astrocyte Activation Involved In Immune Response Clathrin Binding Clathrin-coated Vesicle Membrane Golgi Apparatus Protein Localization To Extracellular Region Protein Secretion Establishment Of Protein Localization To Extracellular Region Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Intracellular Protein Localization Endosome Protein Transport Secretion Positive Regulation Of Regulated Secretory Pathway Vesicle Organization Positive Regulation Of Transport Cytoplasmic Vesicle Membrane Receptor-mediated Endocytosis Endosome To Melanosome Transport Establishment Of Protein Localization Golgi To Lysosome Transport Clathrin-coated Endocytic Vesicle Membrane Clathrin-coated Vesicle
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