CPPED1 and BFAR

		CPPED1	BFAR
Description		calcineurin like phosphoesterase domain containing 1	bifunctional apoptosis regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Azurophil Granule Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Protein Serine/threonine Phosphatase Activity Hydrolase Activity Metal Ion Binding	Protein Binding Zinc Ion Binding Transferase Activity Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity Caspase Binding
	Biological Process		Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process IRE1-mediated Unfolded Protein Response Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of IRE1-mediated Unfolded Protein Response
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Depression ( 29700475) Height ( 31562340) Type 2 diabetes ( 25760438)
Interacting Genes		6 interacting genes: BFAR COQ7 CRYM MRTFB POT1 SHISA9	15 interacting genes: BCL2 CASP10 CASP8 CPPED1 PRKACA SHISA9 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2N UBE2U UBE2W
Entrez ID		55313	51283
HPRD ID		07735	16548
Ensembl ID		ENSG00000103381	ENSG00000103429
Uniprot IDs		Q9BRF8	H3BMP2 Q9NZS9
PDB IDs
Enriched GO Terms of Interacting Partners?		Delta1-piperideine-2-carboxylate Reductase Activity Thiomorpholine-carboxylate Dehydrogenase Activity 3-demethoxyubiquinol 3-hydroxylase Activity 3-demethoxyubiquinone 3-hydroxylase (NADH) Activity Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly Ionotropic Glutamate Receptor Complex Lysine Catabolic Process Thyroid Hormone Binding Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex Single-stranded Telomeric DNA Binding Telomerase Inhibitor Activity Shelterin Complex Establishment Of Protein Localization To Telomere Negative Regulation Of IRE1-mediated Unfolded Protein Response DEAD/H-box RNA Helicase Binding Nuclear Telomere Cap Complex Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding IRE1-mediated Unfolded Protein Response Thyroid Hormone Transport Telomeric Loop Disassembly Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Telomere Capping Caspase Binding Dendritic Spine Membrane Hormone Binding Ubiquinone Biosynthetic Process Regulation Of DNA Strand Elongation Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of Modification Of Postsynaptic Structure Regulation Of Short-term Neuronal Synaptic Plasticity Ubiquinone Metabolic Process Thyroid Hormone Metabolic Process Quinone Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Striated Muscle Tissue Development Regulation Of Modification Of Synaptic Structure Positive Regulation Of Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening	Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Proteolysis Involved In Protein Catabolic Process Proteolysis Modification-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin Protein Ligase Binding Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Macromolecule Catabolic Process Protein Modification Process Protein Metabolic Process Protein K48-linked Ubiquitination Catabolic Process TORC1 Signaling Negative Regulation Of TORC1 Signaling ATP Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process TOR Signaling Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Proteasomal Protein Catabolic Process Cellular Response To Nutrient Levels Nucleotide Binding Transferase Activity Macromolecule Metabolic Process Death Effector Domain Binding Protein K11-linked Ubiquitination Regulation Of TOR Signaling Protein Catabolic Process Ripoptosome CD95 Death-inducing Signaling Complex Protein Monoubiquitination Negative Regulation Of Intracellular Signal Transduction Response To Nutrient Levels Negative Regulation Of Signal Transduction Positive Regulation Of Protein Polyubiquitination Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Cell Communication Positive Regulation Of Execution Phase Of Apoptosis Execution Phase Of Apoptosis Protein K6-linked Ubiquitination Regulation Of Signal Transduction Regulation Of Protein Polyubiquitination Protein-containing Complex DNA Damage Response
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