BFAR

Description		bifunctional apoptosis regulator
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity Caspase Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process IRE1-mediated Unfolded Protein Response Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of IRE1-mediated Unfolded Protein Response
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		15 novel interacting genes: BCL2 CASP10 CASP8 CPPED1 PRKACA SHISA9 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2N UBE2U UBE2W
Interacting Genes		15 interacting genes: BCL2 CASP10 CASP8 CPPED1 PRKACA SHISA9 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2N UBE2U UBE2W
Entrez ID		51283
HPRD ID		16548
Ensembl ID		ENSG00000103429
Uniprot IDs		H3BMP2 Q9NZS9
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Proteolysis Involved In Protein Catabolic Process Proteolysis Modification-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin Protein Ligase Binding Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Macromolecule Catabolic Process Protein Modification Process Protein Metabolic Process Protein K48-linked Ubiquitination Catabolic Process TORC1 Signaling Negative Regulation Of TORC1 Signaling ATP Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process TOR Signaling Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Proteasomal Protein Catabolic Process Cellular Response To Nutrient Levels Nucleotide Binding Transferase Activity Macromolecule Metabolic Process Death Effector Domain Binding Protein K11-linked Ubiquitination Regulation Of TOR Signaling Protein Catabolic Process Ripoptosome CD95 Death-inducing Signaling Complex Protein Monoubiquitination Negative Regulation Of Intracellular Signal Transduction Response To Nutrient Levels Negative Regulation Of Signal Transduction Positive Regulation Of Protein Polyubiquitination Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Cell Communication Positive Regulation Of Execution Phase Of Apoptosis Execution Phase Of Apoptosis Protein K6-linked Ubiquitination Regulation Of Signal Transduction Regulation Of Protein Polyubiquitination Protein-containing Complex DNA Damage Response
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