CPPED1 and CRYM

		CPPED1	CRYM
Description		calcineurin like phosphoesterase domain containing 1	crystallin mu
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Azurophil Granule Lumen	Nucleus Cytoplasm Mitochondrion Peroxisomal Matrix Cytosol Extracellular Exosome
	Molecular Function	Protein Serine/threonine Phosphatase Activity Hydrolase Activity Metal Ion Binding	Transcription Corepressor Activity Protein Binding Oxidoreductase Activity Hormone Binding Protein Homodimerization Activity Delta1-piperideine-2-carboxylate Reductase Activity Thiomorpholine-carboxylate Dehydrogenase Activity NADP Binding Thyroid Hormone Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process Sensory Perception Of Sound Thyroid Hormone Metabolic Process Thyroid Hormone Transport
Pathways		Neutrophil degranulation	Lysine catabolism
Drugs			NRP409
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Depression ( 29700475) Height ( 31562340) Type 2 diabetes ( 25760438)	Pelvic organ prolapse ( 26545240)
Interacting Genes		6 interacting genes: BFAR COQ7 CRYM MRTFB POT1 SHISA9	6 interacting genes: ADRB2 C7orf25 CDC37 CPPED1 TERF1 TG
Entrez ID		55313	1428
HPRD ID		07735	08831
Ensembl ID		ENSG00000103381	ENSG00000103316
Uniprot IDs		Q9BRF8	Q14894
PDB IDs			2I99
Enriched GO Terms of Interacting Partners?		Delta1-piperideine-2-carboxylate Reductase Activity Thiomorpholine-carboxylate Dehydrogenase Activity 3-demethoxyubiquinol 3-hydroxylase Activity 3-demethoxyubiquinone 3-hydroxylase (NADH) Activity Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly Ionotropic Glutamate Receptor Complex Lysine Catabolic Process Thyroid Hormone Binding Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex Single-stranded Telomeric DNA Binding Telomerase Inhibitor Activity Shelterin Complex Establishment Of Protein Localization To Telomere Negative Regulation Of IRE1-mediated Unfolded Protein Response DEAD/H-box RNA Helicase Binding Nuclear Telomere Cap Complex Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding IRE1-mediated Unfolded Protein Response Thyroid Hormone Transport Telomeric Loop Disassembly Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Telomere Capping Caspase Binding Dendritic Spine Membrane Hormone Binding Ubiquinone Biosynthetic Process Regulation Of DNA Strand Elongation Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of Modification Of Postsynaptic Structure Regulation Of Short-term Neuronal Synaptic Plasticity Ubiquinone Metabolic Process Thyroid Hormone Metabolic Process Quinone Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Striated Muscle Tissue Development Regulation Of Modification Of Synaptic Structure Positive Regulation Of Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening	Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Positive Regulation Of Macroautophagy Beta2-adrenergic Receptor Activity Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication HSP90-CDC37 Chaperone Complex Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Response To Psychosocial Stress Positive Regulation Of Autophagy Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Regulation Of Macroautophagy Positive Regulation Of Autophagosome Maturation Heat Generation Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Shelterin Complex Ankyrin Repeat Binding Iodide Transport Adrenergic Receptor Activity Nuclear Telomere Cap Complex Telomere Localization Meiotic Telomere Clustering Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Diet Induced Thermogenesis G-rich Strand Telomeric DNA Binding Adenylate Cyclase Binding Negative Regulation Of Smooth Muscle Contraction T-circle Formation Telomeric Loop Disassembly Telomere Capping Positive Regulation Of Type 2 Mitophagy Negative Regulation Of Multicellular Organism Growth Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Thyroid Hormone Generation Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction DNA Binding, Bending
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