TTC38 and PRR5

		TTC38	PRR5
Description		tetratricopeptide repeat domain 38	proline rich 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Cytosol TORC2 Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Cytoskeleton Organization Positive Regulation Of Cell Growth Cellular Response To Nutrient Levels TORC2 Signaling Negative Regulation Of Apoptotic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways			PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs
Diseases
GWAS		Urinary metabolite levels in chronic kidney disease ( 31959995)	Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)
Interacting Genes		3 interacting genes: PFDN1 PRR5 TK1	8 interacting genes: CTNNA3 DESI1 GPSM3 HGS SCUBE1 TTC38 USHBP1 WNT7B
Entrez ID		55020	55615
HPRD ID		07943	18696
Ensembl ID		ENSG00000075234	ENSG00000186654
Uniprot IDs		Q5R3I4	P85299
PDB IDs
Enriched GO Terms of Interacting Partners?		Prefoldin Complex DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Thymidine Kinase Activity Deoxyribonucleoside Monophosphate Biosynthetic Process TORC2 Complex Pyrimidine Nucleoside Metabolic Process Negative Regulation Of Amyloid Fibril Formation TORC2 Signaling Regulation Of Amyloid Fibril Formation Pyrimidine-containing Compound Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Nucleoside Metabolic Process	Chemoattraction Of Dopaminergic Neuron Axon Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Lobar Bronchus Development Trachea Cartilage Morphogenesis Renal Outer Medulla Development Outer Medullary Collecting Duct Development Bronchus Development Chemoattraction Of Axon Metanephric Loop Of Henle Development Inner Medullary Collecting Duct Development Renal Inner Medulla Development ESCRT-0 Complex
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