PRR5

Description		proline rich 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol TORC2 Complex
	Molecular Function	Protein Binding
	Biological Process	Cytoskeleton Organization Positive Regulation Of Cell Growth Cellular Response To Nutrient Levels TORC2 Signaling Negative Regulation Of Apoptotic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)
Novel Interacting Genes		8 novel interacting genes: CTNNA3 DESI1 GPSM3 HGS SCUBE1 TTC38 USHBP1 WNT7B
Interacting Genes		8 interacting genes: CTNNA3 DESI1 GPSM3 HGS SCUBE1 TTC38 USHBP1 WNT7B
Entrez ID		55615
HPRD ID		18696
Ensembl ID		ENSG00000186654
Uniprot IDs		P85299
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemoattraction Of Dopaminergic Neuron Axon Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Lobar Bronchus Development Trachea Cartilage Morphogenesis Renal Outer Medulla Development Outer Medullary Collecting Duct Development Bronchus Development Chemoattraction Of Axon Metanephric Loop Of Henle Development Inner Medullary Collecting Duct Development Renal Inner Medulla Development ESCRT-0 Complex
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