PKNOX1 and RAB11FIP4

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		PKNOX1	RAB11FIP4
Description		PBX/knotted 1 homeobox 1	RAB11 family interacting protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Extracellular Space Cytoplasm Endosome Golgi Apparatus Centrosome Spindle Cytoskeleton Membrane Endocytic Vesicle Midbody Cytoplasmic Vesicle Cleavage Furrow Perinuclear Region Of Cytoplasm Recycling Endosome Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Angiogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Hemopoiesis T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II	Neural Retina Development Endocytic Recycling Regulation Of Cytokinesis Positive Regulation Of G1 To G0 Transition
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)	Adventurousness ( 30643258) Apolipoprotein A1 levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Facial attractiveness (male raters) ( 30946739) Heel bone mineral density ( 28869591 30598549) Hip circumference adjusted for BMI ( 34021172) Keratoconus ( 33649486) Myocardial infarction ( 33532862)
Interacting Genes		58 interacting genes: ANKRD49 APC APP ARL13B BAIAP2 BEX4 BLOC1S5 BORCS6 BRD2 C1S CAPRIN1 CMYA5 EEF1A2 EXOC7 FAM110B FHL2 FIBP FMNL2 GAS7 HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 ITGB3BP KIF1A KIF1B MACF1 MEIS1 MPP3 MX2 NRIP1 NUP58 PAX6 PBX1 PBX2 PBX3 PCNT PFDN2 POU2F1 PRSS3 RAB11FIP4 RFX3 RNF40 SPTBN1 STAT1 STAT6 SYNM TCOF1 TEKT4P2 TET2 TLX1 TRIM59 TTC3 UBR1 VPS37C WIZ ZBTB3	10 interacting genes: ARF6 ECPAS GFI1B IFT20 MAD2L2 PKNOX1 RAB11A RAB11FIP2 RAB11FIP3 RAB11FIP5
Entrez ID		5316	84440
HPRD ID		03653	11466
Ensembl ID		ENSG00000160199	ENSG00000131242
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87	Q86YS3
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?		Pattern Specification Process Positive Regulation Of Transcription By RNA Polymerase II Chromatin DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Regionalization Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Embryonic Morphogenesis Regulation Of RNA Metabolic Process Microtubule Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Animal Organ Morphogenesis Eye Development Regulation Of Nucleobase-containing Compound Metabolic Process Microtubule-based Transport Nucleus Proximal/distal Pattern Formation Retrograde Neuronal Dense Core Vesicle Transport DNA Binding Axo-dendritic Transport Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Organelle Transport Along Microtubule Transport Along Microtubule Positive Regulation Of Biosynthetic Process Neuron Development Sensory Organ Development Positive Regulation Of Macromolecule Metabolic Process Regulation Of Dendritic Spine Morphogenesis Dense Core Granule Cytoskeletal Transport Transcription Coregulator Binding Anterograde Axonal Transport Regulation Of Metabolic Process Vesicle Transport Along Microtubule Positive Regulation Of Metabolic Process Cytoskeleton-dependent Intracellular Transport Regulation Of Gene Expression Transcription Corepressor Binding	Protein Localization To Cleavage Furrow Recycling Endosome Membrane Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Recycling Endosome Positive Regulation Of Cilium Assembly Endosome Vesicle Docking Involved In Exocytosis Positive Regulation Of Cytokinesis Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Adiponectin Secretion Protein Localization To Plasma Membrane Early Endosome To Recycling Endosome Transport Cleavage Furrow Vesicle Docking Protein Localization To Cilium Regulation Of Cell Projection Assembly Mitotic Cytokinesis Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Plasma Membrane Endocytic Vesicle Positive Regulation Of Protein Localization To Cell Periphery Protein Transport Endocytic Recycling Organelle Localization By Membrane Tethering Regulation Of Cytokinesis Small GTPase Binding Positive Regulation Of Protein Localization To Membrane Membrane Docking Positive Regulation Of Cell Division Cytoskeleton-dependent Cytokinesis Establishment Of Cell Polarity Protein Localization To Membrane Regulation Of Protein Localization To Centrosome Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Organelle Assembly Regulation Of Cilium Assembly Establishment Of Protein Localization Regulation Of Cell Cycle Process Positive Regulation Of Cell Projection Organization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Protein Localization To Plasma Membrane Vesicle-mediated Transport To The Plasma Membrane Regulation Of Endocytic Recycling Regulation Of Protein Transport Establishment Of Localization In Cell Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization Establishment Or Maintenance Of Cell Polarity
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